| 李银平秦俭王晶江利王涛.乳酸和APACHE II 评分在评估老年脓毒症患者预后中的应用[J].,2011,11(12):2273-2275 |
| 乳酸和APACHE II 评分在评估老年脓毒症患者预后中的应用 |
| Evaluation of Prognosis of Elderly Patients with Sepsisby Lactic Acid and APACHE II Scores |
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| DOI： |
| 中文关键词: 乳酸 APACHE II 评分 脓毒症 老年 预后 |
| 英文关键词: Lactic acid Acute Physiology And Chronic Health Evaluation II Sepsis elderly prognosis |
| 基金项目: |
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| 中文摘要: |
| 目的：研究乳酸和急性生理学及慢性健康状况评分（APACHE II 评分）对老年脓毒症患者预后的评估作用。方法：老年脓毒症
患者96 例，按照入院时血乳酸值分成升高者60 例，乳酸正常者36 例，比较两组的病死率、休克、机械通气和MODS 发生率、
APACHE II 评分的区别；根据APACHE II 评分(<15、15～24、≥25)分为3 组，比较每组患者的病情和预后区别。结果：乳酸升高组
老年脓毒症患者的机械通气、休克发生率、MODS 发生率、APACHE II 评分明显大于乳酸正常组(P<0.05)，病死率明显上升(28.3％
vs 2.7％)，(P=0.005)；随着APACHE II 评分增高，患者病情逐渐加重，休克发生率和住院病死率明显升高，(P<0.05)，患者乳酸水平
也明显增高(P<0.05)。结论：血乳酸和APACHE II 评分都可以评估老年脓毒症患者病情严重和预后，两者升高提示预后差。 |
| 英文摘要: |
| Objective: To study the evaluation prognosis function of lactic acid and acute and chronic physiology health score II
(APACHE II score) in elderly patients with sepsis. Methods: The Clinical data of 96 elderly patients with sepsis were collected,60 cases
with elevated blood lactic acid and 36 cases with normal lactic acid, the difference of mortality, shock,mechanical ventilation and MODS
incidence,APACHE II score were compared between 2 groups;According to APACHE II score (＜15 scores,15～24 scores,≥25 scores),
the patients were divided into three groups,the difference of condition and prognosis were compared among each group. Results: The
mechanical ventilation,shock,MODS, APACHE II score in elderly septic patients with elevated lactate were significantly higher than that
in normal lactic acid group(P<0.05),mortality significantly increased(28.3% vs 2.7%,P=0.005);With the APACHE II score increased,the
patient's illness was gradually worsened,shock incidence and hospital mortality were increased significantly,(P<0.05) ,lactic acid levels
were significantly higher in patients (P<0.05).Conclusion: The lactic acid levels and APACHE II score can effectively assess the patients
condition and prognosis;The elderly sepsis patients with elevated blood lactate had a serious condition and poor prognosis. |
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