文章摘要
杨燕1 刘会玲2 虎镯3 高飞艳4 杨毓琴2.兰州地区女性感染HPV及其基因类型分析[J].,2011,11(21):4069-4071
兰州地区女性感染HPV及其基因类型分析
Study on the Human Papillomavirus (HPV) Infection and GenotypesDistribution Pattern ofWomen in Lanzhou Area
  
DOI:
中文关键词: 人乳头瘤病毒(HPV)  分型  PCR
英文关键词: Human papillomavirus (HPV)  Genotyping  PCR
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作者单位
杨燕1 刘会玲2 虎镯3 高飞艳4 杨毓琴2 兰州大学第一临床医学院 
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中文摘要:
      目的:了解兰州地区成年女性感染人乳头瘤病毒( human pap illoma virus, HPV)及其基因类型分布状况,为本地区HPV 分子 流行病学研究提供理论依据。方法:利用PCR技术分别对100例妇科门诊就诊者进行HPV基因亚型检测。结果:100例样品中, HPV DNA检出率为19%(19/100),其中HPV16 DNA感染率15%(15/100),HPV58 DNA 感染率3%(3/100),HPV18 DNA 感染率 2%(2/100),HPV 16与HPV18双重感染1例。结论:本地区成年女性HPV 感染主要以HPV16 多见,而HPV16 与恶性肿瘤密切 相关,因此对HPV DNA阳性者定期随访,有利于宫颈癌的防治。
英文摘要:
      Objective: This is an epidemiological study on the distribution pattern of HPV genolypes in Lanzhou area. Methods: One hundred samples were detected for HPV genotyping by using PCR technique. Results: In 100 samples, the positive rate of HPV DNA was 19%. HPV16 DNA was 15 % (15/100). HPV58 DNA was 3%(3/100) and HPV18 DNA was 2 %(2/100). And one case infected both HPV16 and HPV18. Conclusion: The most prevalent HPV genotypes in Lanzhou area were HPV 16 which is closely related with the malignancy. Therefore peoples who suffered HPV DNA positive should be regularly followed-up, which is useful for the prevention and treatment of cervical cancer.
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