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目的：探讨肝移植后急性肺损伤（ALI）的相关因素，为肝移植术后ALI的预防和治疗提供参考。方法：回顾性分析了2005年 1月~2010年10月在我院行肝移植术的98例患者的临床资料，对术后并发ALI的相关因素进行分析。结果：98 例行肝移植术后发生ALI 12 例，发生率为12.24%。单因素分析显示年龄、术前血清TBIL、术中失血量、术中尿量和术后血BUN 对ALI的发生有显著影响（P<0.05）。多因素Logistic 回归法分析表明，术中失血量、术前TBIL、年龄为术后并发ALI的危险因素。结论：术中失血量、术前TBIL、年龄为术后并发ALI的危险因素，对上述因素加以重点评估和合理控制，可以控制肝移植术后ALI的发生。

英文摘要:

Objective: To investigate the related factors in patient with acute lung injury (ALI) after liver transplantation and provide reference for prevention and treatment of ALI after liver transplantation. Methods: The clinical data of 98 cases from the patients undergoing rothotopic liver transplantation was reviewed from January 2005 to October 2010, analyzing and screening the related factors of ALI after liver transplantation by Logistic. Results: 12 cases of 98 patients occurred ALI, the incidence rate of ARF was 12.24%. The single-factor analysis showed that the age, preoperative serum TBIL, intraoperative blood loss, intraoperative urine output and postoperative BUN had certain degree of contact with the incidence of ALI after liver transplantation (P<0.05). Multivariate Logistic regression analysis showed that the intraoperative blood loss, preoperative serum TBIL and age were risk factors of incidence of ALI after liver transplantation. Conclusion: The age, preoperative serum TBIL, intraoperative blood loss, intraoperative urine output and postoperative BUN are the related factors of incidence of ALI after liver transplantation. The intraoperative blood loss, preoperative serum TBIL and age were risk factors of incidence of ALI after liver transplantation. Assessment and control these factors can reduce the incidence of ALI after liver transplantation.

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