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目的：比较不同时期颈髓损伤的MRI表现及DTI的应用价值。方法：收集急性颈髓压迫病例15 例、慢性颈髓压迫病例23 例、颈髓慢性压迫合并急性压迫病例12例。15例健康志愿者作为对照组。进行常规MRI检查，应用DTI检查测量表观扩散系数（ADC）值和各向异性分数(FA)。比较各组间ADC值和FA值，并进行统计学分析。结果：急性颈髓迫病例，常规MRI显示颈髓增粗，呈等T1 长T2 信号；慢性颈髓压迫病例，9 例呈长T1 长T2 信号，14 例呈等T1 长T2 信号；慢性颈髓压迫并急性压迫病例颈髓明显增粗，呈等、长T1 明显长T2 信号。与对照组比较：急性颈髓压迫组的ADC值和FA值均明显降低，两组的差异有显著性；慢性颈髓压迫组的FA 值降低，ADC 值增高，两组的差异有显著性；慢性脊髓压迫合并急性脊髓压迫组ADC 值与对照组比较无差异，FA值低于对照组。颈髓压迫各组间ADC值及FA值比较差异显著。结论：不同时期颈髓损伤常规MRI图像缺乏特异性，根据ADC值及FA值可判断颈髓损伤的时期。

英文摘要:

Objective: Compared the features of conventional MRI and the values of DTI in the cervical cord injure different stages. Methods: The patients were divided three groups: acute cervical cord injure(n=15), chronic cervical cord injure (n=23)and chronic cervical cord injure with acute injure (n=12); 15 healthy volunteers is control group. All of the patients and control group had conventional MRI scan and MRI-DTI scan. Compared the features of MRI and the values the ADC and FA in the different groups. Results: There are isointensity on T1WI and hyperintensity on T2WI, the injured cervical cord became swelling in acute injure group. The signal is isointensity or hypointensity on T1WI and hyperintensity on T2WI in chronic stage. The features of MRI in chronic stage with the acute injure is the same as the chronic stage. Compared with the control group,the value of ADC and FA decreas significantly in acute cervical cord injure group, the value of ADC increas and the value of the FA decrease in chronic cervical cord injure group, the value of ADC has not change and the value of the FA decrease in the chronic cervical cord injure with acute injure. The value of ADC and FA are different in the cervical cord injure different stages. Conclusion: The conventional RI is absent of typical features in different stage of cervical cord injure.However, the value of ADC and FA can manifest the stage of cervical cord injure.

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