| 代忠1 于洁2 孙健1 赵红艳1 张丹1 田立霞1.榄香烯联合GP 化疗方案治疗晚期肺腺癌脑转移的临床观察[J].,2012,12(2):320-323 |
| 榄香烯联合GP 化疗方案治疗晚期肺腺癌脑转移的临床观察 |
| Clinical observation of Elemene combined with Gemcitabine and Cisplatinon treating brain metastases of advanced lung adenocarcinoma |
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| DOI： |
| 中文关键词: 榄香烯注射液 GP 化疗方案 晚期肺腺癌脑转移 营养支持 |
| 英文关键词: Elemene injection Gemcitabine and Cisplatin treatment Brain metastases of advanced lung adenocarcinoma Nutritional
support |
| 基金项目: |
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| 中文摘要: |
| 目的：观察中药制剂榄香烯联合GP 化疗方案治疗晚期肺腺癌脑转移的疗效。方法：选取2009 年6 月28 日至2011 年5 月
30 日就诊于我院的晚期肺腺癌脑转移患者34 例，将34 例晚期肺腺癌脑转移患者随机分为两组（A 组和B 组），A 组：治疗组，17
例，并给予患者榄香烯静脉滴注和GP 化疗方案；B 组：对照组，17 例，给予患者GP 化疗方案；观察两组疗效和安全性，并记录治
疗前后相关的指标变化。结果：2 个疗程的化疗结束后，A 组：10 例患者复查脑核磁发现脑转移瘤较前缩小，病灶部分缓解（P R）；6
例脑转移瘤病灶稳定（SD）；1 例疾病进展（PD）；B 组：5 例患者复查脑核磁发现脑转移瘤较前缩小，病灶部分缓解（P R）；9 例脑转
移瘤病灶稳定（SD）；3 例疾病进展（PD）。结论：采用榄香烯联合GP 化疗方案治疗晚期肺腺癌脑转移，能有效地改善患者生活质
量，疗效满意。 |
| 英文摘要: |
| Objective: To observe the curative effect of Elemene combined with Gemcitabine and Cisplatin on treating brain metastases
of advanced lung adenocarcinoma. Methods: 34 patients were chosen and were brain metastases of advanced lung adenocarcinoma.
The patients were randomly divided into two groups (group A and group B). The patients in group A were treated with Elemene combined
with Gemcitabine and Cisplatin, and the others were only treated with Gemcitabine and Cisplatin. Recording the effect and safety
after treatment. Results: After 2 pe- riods of treatment, group A: 10 cases were evaluated as PR, 6 SD and 1 PD; group B: 5 cases were evaluated
as PR, 9 SD and 3 PD. Conclusion: It is positive to treat the brain metastases of advanced lung adenocarcinoma with Elemene
combined with Gemcitabine and Cisplatin. |
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