| 仇波1 彭悦1 邓亚平2 刘志红2 曾亮2.宫颈癌患者液基细胞学与组织学诊断的比较分析
仇[J].,2012,12(3):501-503 |
| 宫颈癌患者液基细胞学与组织学诊断的比较分析
仇 |
| The Comparative Analysis of Liquid Based Cytology Diagnosis andHistological Diagnosis in 83 Cases of Cervical Squamous Cell Carcinoma |
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| DOI： |
| 中文关键词: 宫颈癌 液基细胞学 组织学 |
| 英文关键词: Cervical cancer Liquid based cytology Histology |
| 基金项目: |
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| 摘要点击次数: 692 |
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| 中文摘要: |
| 目的：通过对液基细胞学检测（TCT）与组织学活检的比较分析，探讨TCT 出现漏诊的原因。方法：收集83 例宫颈癌患者的
宫颈活检组织蜡块和宫颈脱落细胞标本，组织蜡块行常规病理切片检查，脱落细胞标本进行TCT 检测。结果：和组织病理学诊断
结果比较，这些患者的TCT 诊断漏诊18 例。进行过抗HPV 治疗的宫颈癌患者，其TCT 漏诊率明显高于未治疗者（P＜0.05）。结
论：TCT 在宫颈癌筛查中存在一定的漏诊，其产生的原因与癌细胞分化程度、宫颈糜烂程度、非诊断细胞的干扰、不当的采集方法
及抗HPV 治疗有关。 |
| 英文摘要: |
| Objective: To explore the causes of the errors of liquid based cytology test , through a comparative analysis of liquid
based cytology test and histology of biopsy. Methods: The paraffin blocks of cervical biopsies and the cervical cytology specimens of 83
cases of cervical carcinoma were collected, the paraffin blocks were for routine HE staining and histological diagnosis, the cytology
specimens were dectected with liquid based cytology test and diagnosis. Results: Compared to histological diagnosis, the diagnosis in the
liquid based cytology of these patients showed that 18 cases were missed diagnosed. The rate of misdiagosis of these patients who had
been regularly anti-HPV treated was significantly higher than that of the others (P<0.05). Conclusion: There were some errors in liquid
based cytology test in cervical cancer screening , the reasons associated with the cell differentiation ,the degree of cervical erosion, the
interference from non-diagnostic cells , the improper collection method and that the patients had been regularly anti-HPV treated . |
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