| 李娜1 郭晓东2 刘润梅1 翟红霞1 殷亚昕1 李良1 张津津1
陈海威1 王磊1 夏云峰1△.苯磺酸氨氯地平和厄贝沙坦对老年高血压病患者血压及
血压变异性的影响[J].,2012,12(12):2356-2358 |
| 苯磺酸氨氯地平和厄贝沙坦对老年高血压病患者血压及
血压变异性的影响 |
| Effect of Amlodipine Besylate and Irbesartan on Blood PressureVariability in Elder Patients with Hypertension |
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| 中文摘要: |
| 目的：比较苯磺酸氨氯地平和厄贝沙坦对老年高血压病患者血压及24 小时动态血压变异性的影响。方法：研究140 例年龄
在60～75 岁之间的患者随机分为A、B 两组，每组各70 例，A 组予以服用苯磺酸氨氯地平片（5mg/d）、B 组予以厄贝沙坦片
(150mg/d)，对两组病人进行服药前及服药4 周后24 小时动态血压检查，比较两种药物对血压及24 小时动态血压变异性的影响。
结果：①两种降压药物均能有效降低血压(P<0.05)。②在控制24 小时血压变异性方面，苯磺酸氨氯地平优于厄贝沙坦(P<0.05)。
结论：与厄贝沙坦相比，苯磺酸氨氯地平能更理想的控制血压变异性。 |
| 英文摘要: |
| Objective: To investigate the effect of Amlodipine Besylate and Irbesartan on blood pressure variability in elder
patients with hypertension. Methods：140 patients with 1 level hypertension were divided into two groups of A and B,each group of each
70 patients,and patients in group A orally took 5mg/d Amlodipine Besylate once daily,while group B orally took 150mg/d Irbesartan
tablets once daily,24 hours ambulatory blood pressure monitoring were performed before and after 4 weeks treatment,and compared the
influence of two drugs on blood pressure and 24 hours blood pressure variability (BPV). Results：① After treatment,each group's blood
pressure is lower than before treatment,the difference has statistics significance (P<0.05). ②Comparing the influence on 24 hours blood
pressure variability of two groups, group A is better than group B (P<0.05). Conclusion：Both Amlodipine Besylate and Irbesartan can
control 1 level hypertension, and Amlodipine Besylate is better than Irbesartan on 24 hours BPV. |
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