| 杨文思1 王洋2.艾滋病治疗药物--HIV 抑制剂作用机制及研究进展[J].,2012,12(23):4560-4562 |
| 艾滋病治疗药物--HIV 抑制剂作用机制及研究进展 |
| Anti-AIDS drugs--HIV Inhibitors: Function Mechanism and ResearchProgress |
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| DOI： |
| 中文关键词: 艾滋病 HIV HIV 抑制剂 |
| 英文关键词: AIDS HIV HIV inhibitor |
| 基金项目: |
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| 中文摘要: |
| 艾滋病（AIDS）是由人类免疫缺陷病毒（HIV）感染而引起的慢性进行性致死性传染病，又称获得性免疫缺陷综合症，目前无
有效治愈的方法，严重危害着人类的健康。现今，艾滋病治疗药物主要包括逆转录酶抑制剂、蛋白酶抑制剂、进入抑制剂、整合酶
抑制剂四大类化学药物和一些中草药制剂。抗HIV 药物虽然不能完全治愈艾滋病，但可以控制艾滋病病情的发展，延长患者的无
病生存期，提高患者的生活质量。本文就艾滋病发病机制、HIV 抑制药物的抗病机制、副作用及其研究进展做一综述。 |
| 英文摘要: |
| AIDS or Acquired Immune Deficiency Syndrome is a progressive and fatal contagious disease caused by human
immunodeficiency virus （HIV）. Currently, as an incurable disease, AIDS became a serious public health problem in the whole world. At
present, anti-AIDS drugs are mainly belong to HIV inhibitors, including inhibitors of reverse transcriptase, protease, integrase and entry
inhibitors, as well as some Chinese herbal medicines. Although these anti-HIV drugs can not cure AIDS, it may enhance patient 's life
quality and prolong disease free survival. This article will review the function mechanism, by-effect and research progress of HIV
inhibitors. |
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