| 陈英杰刘恒陈强梁宁震.化疗联合DC 和CIK方案治疗非小细胞肺癌的临床疗效观察[J].,2014,14(2):323-325 |
| 化疗联合DC 和CIK方案治疗非小细胞肺癌的临床疗效观察 |
| The Clinical Effect Observation of Chemotherapy Combined with DC andCIK for the Treatment of Non-small Cell Lung Cancer |
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| DOI： |
| 中文关键词: 树突状细胞 细胞因子诱导的杀伤细胞 非小细胞肺癌 化疗 |
| 英文关键词: Dendritic cells (DC) Cytokine-induced killer cells (CIK) Non-small cell lung cancer Chemotherapy |
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| 中文摘要: |
| 摘要目的：探讨化疗联合树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗非小细胞肺癌的临床疗效。方法：随机选取
2008年10月份-2011 年02 月份因非小细胞肺癌就诊于我院进行治疗的患者120 例，随机分为治疗组60 例患者（采用化疗联合
树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗），对照组60 例患者（采用常规化疗），统计两组患者的治疗效果以及
生活质量情况，并对结果进行统计分析。结果：治疗组患者治疗总有效率为68.4%，生活质量提高率为88.4%，明显好于与对照组，
经统计分析，P<0.05，差异存在显著性。结论：化疗联合树突状细胞(DC)和细胞因子诱导的杀伤细胞(CIK)方案治疗非小细胞肺癌
能够显著改善患者的生活质量，是治疗非小细胞肺癌的有效方法。 |
| 英文摘要: |
| ABSTRACT Objective：To discuss the clinical effect of chemotherapy combined with dendritic cells (DC) and cytokine-induced
killer cells (CIK) for the treatment of non-small cell lung cancer. Methods：From October, 2008 to February 2011, 120 patients with
non-small cell lung cancer were randomly divided into treatment group （chemotherapy combined with dendritic cells (DC) and
cytokine-induced killer cells (CIK) group, n=60）and control group （conventional chemotherapy group, n=60）. We summarized the
curative effect and the quality of life of patients and made a statistical analysis for the results.Results： In the treatment group, the total
effective rate was 68.4%, the improvement rate of the quality of life was 88.4%. It was significantly better when compared with the
control group. After the statistical analysis, P<0.05, there were significant differences. There was a significant difference in statistics.
Conclusion：Chemotherapy combined with dendritic cells (DC) and cytokine-induced killer cells (CIK) for the treatment of non-small cell
lung cancer can improve the quality of life for the patient. It is a effective method for the treatment of non-small cell lung cancer. |
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