| 王秋程1 程文1△ 张翠1 孙一欣1 邢长宏2 毕玉美1.超声造影引导下行微波消融术治疗肝癌的临床效果分析*[J].,2014,14(8):1532-1535 |
| 超声造影引导下行微波消融术治疗肝癌的临床效果分析* |
| Clinical Analysis of Microwave Ablation on the Treatment of HepatocellularCarcinoma with Contrast-enhanced Ultrasound* |
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| DOI： |
| 中文关键词: 超声造影 肝癌 微波消融 常规超声 |
| 英文关键词: Contrast-enhanced ultrasound Hepatocellular carcinoma Microwave ablation Conventional ultrasound |
| 基金项目:黑龙江省自然科学基金项目（D201170） |
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| 中文摘要: |
| 摘要目的：评估超声造影(CEUS)引导下微波消融(MWA)治疗肝癌的有效性及应用价值。方法：108 例肝癌患者，共147个病灶经
MWA治疗。根据患者在做常规超声检查时，是否有扫查不清晰的结节或其他影像学检查提示可能存在多发结节等，分成CEUS
族和对照组。CEUS组41 名患者,年龄(57.9± 7.8）岁，共57 个病灶,平均直径（2.4± 1.5）cm，经超声造影引导下行微波消融治疗。
对照组67 名患者，年龄（55.5± 8.9）岁，共90 个病灶,平均直径（2.6± 1.7）cm，常规超声引导下同种条件行微波消融治疗。治疗后
对两组患者进行6～12 个月随访。结果：CEUS组的57 个病灶均清晰显示其位置、数目、大小、边界、形态，完全消融的结节为55
个,未完全消融的结节为2个。对照组67 名患者的90 个病灶，完全消融的病灶78 个；未完全消融的结节12 个。CEUS组完全消
融率高于病例对照组(96.49 %VS 86.67 %；P< 0.05）。随访6～12 个月后发现，CEUS 组完全消融率高于病例对照组(P< 0.05），差
异有统计学意义。结论：CEUS能更好的显示病灶的位置、数目、大小，更精确显示病灶边界、范围，造影引导下MWA 是一种有效
提高完全消融效率的方法，具有较大应用价值。 |
| 英文摘要: |
| ABSTRACT Objective:To assess the clinical effects and value of microwave ablation (MWA) on the treatment of hepatocellular
carcinoma under the assistance of the contrast-enhanced ultrasound (CEUS).Methods:108 patients with hepatocellular carcinoma were
involved in this study. CEUS group including 41 patients with 57 lesions were treated by CEUS-guided MWA. Control group including
67 patients with 90 lesions were treated by MWA guided under conventional ultrasound. Mean diameters of the lesions in the two groups
were (2.4± 1.5) cm and (2.6± 1.7) cm, respectively. MWA were performed on CEUS or conventional ultrasound with the patients under
unconscious intravenous general anaesthesia. The follow-up time were 6-12 months of two groups of patients after treatment. Results:In
the CEUS group, the location, number, size, margin and shape of the 57 lesions were identified clearly on CEUS. 55 (96.49%, 55/57)
lesions were completely treated and 2(3.50 %, 2/57) lesions were incompletely treated by MWA. In the case-control group, there were 78
(86.67 %, 78/90) lesions completely treated and 12 (13.33%, 12/90) lesions were incompletely treated. The ratio of complete ablation in
the CEUS group is higher than that in case-control group (P=0.048).Conclusion: CEUS is more sensitive of presenting the location,
number, size, invasive range and micro-vessel of the lesions that should be an efficient and feasible method for MWA on the treatment of
patient with hepatocellular carcinoma. |
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