| 张立 张雪蓉 王进忠 章雪溪 李雪.不同麻醉方式对老年肺肿瘤患者术后早期认知功能的影响[J].,2014,14(21):4117-4119 |
| 不同麻醉方式对老年肺肿瘤患者术后早期认知功能的影响 |
| Effects of Different Anesthesia Methods on the Cognitive Function forElderly Patients with Lung Cancer |
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| DOI： |
| 中文关键词: 麻醉 肺肿瘤 老年患者 认知功能 |
| 英文关键词: Anesthesia Lung cancer Elderly patients Cognitive function |
| 基金项目:国家自然科学基金项目（3002011801） |
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| 中文摘要: |
| 目的：探讨不同麻醉选择对老年肺肿瘤术后患者早期认知功能的影响。方法：分析我院2011 年3 月至2013 年3 月老年肺
肿瘤患者，分别有62 例用全凭静脉麻醉和61例用静吸复合麻醉的麻醉方法，记录手术时间和麻醉时间，用MMSE 量表进行认知
功能评分，分别评定手术前1 天和手术后出麻醉室时及1、3、5 天患者的认知功能，并判断患者的POCD。结果：两组患者在手术
时间和麻醉时间方面无统计学差异。与术前1 天比较，全凭静脉麻醉组、静吸复合麻醉组出麻醉恢复室时、术后1 d时MMSE 评
分降低(P<0.05)；与术前1 d 比较，两组在术后3 天和7 天时MMSE评分恢复正常（P>0.05），两组患者之间的MMSE 认知功能评
分在术前、术后均无统计学差异（P>0.05），出麻醉恢复室时，全凭静脉麻醉组发生POCD24 例(39.34%) ，全凭静脉麻醉组发生25
例(40.32% )，两组发生率比较无统计学差异（P>0.05）；术后1 天、3 天、7 天两组分别POCD 的发生率比较均无统计学意义（P>0.
05）。结论：老年患者用全凭静脉麻醉、静吸复合麻醉不同麻醉方法对老年患者术后早期发生认知功能障碍的影响无统计学差异。 |
| 英文摘要: |
| Objective:To investigate the effects of different anesthesia methods on the cognitive function of elder patients with
lung cancer.Methods:62 cases with lung cancer patients with total intravenous anesthesia and other 61 patients with complexed anesthesia
of intravenous anesthesia and inhalation anesthesia who were treated in our hospital from March 2011 to March 2013 were selected.
Then the time of operation and anesthesia was recorded. MMSE scale was applied to recording the cognitive function at the first day, the
1, 3, 5 day after the surgery and POCD of patients was compared.Results:There was no statistically significance about the time for the
operation and anesthesia. Compared with 1 day before operation, MMSE scores of both groups before surgery and in anesthesia recovery
roomdecreased (P<0.05); MMSE scores of both groups at 3, 7 days after surgery remained the same (P>0.05). There was no statistically
significant difference between two groups on MMSE cognitive function scoring (P>0.05). In anesthesia recovery room, 24 cases had
POCD in the total intravenous group (39.34%), 25 cases had POCD in total intravenous group (40.32%), there was no significant difference
between two groups (P>0.05); There was no significant difference on POCD occurrence rate at 1,3,7 days after surgery(P>0.05).Conclusion:There is no statistically significant difference between intravenous anesthesia and complexed anesthesia of intravenous
anesthesia and inhalation anesthesia affecting in cognitive function in post-operative elderly patients. |
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