文章摘要
邢宝继 陈林 郭汝涛 刘世伟 冉浩男.应用KV-CBCT分析鼻咽癌调强放射治疗的摆位误差[J].,2014,14(35):6953-6955
应用KV-CBCT分析鼻咽癌调强放射治疗的摆位误差
Setup Error in IntensityModulated Radiotherapy for NasopharyngealCarcinoma by Kilo-Volt Cone-BeamComputed Tomography
  
DOI:
中文关键词: 鼻咽癌  KV-CBCT  调强放射治疗  摆位误差
英文关键词: Nasopharyngeal carcinoma(NPC)  KV-CBCT  Intensity Modulated Radiotherapy(IMRT)  Setup error
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作者单位
邢宝继 陈林 郭汝涛 刘世伟 冉浩男 哈尔滨医科大学附属肿瘤医院放疗科 
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中文摘要:
      目的:应用KV-CBCT 分析鼻咽癌调强放射治疗时的摆位误差,为鼻咽癌调强放射治疗计划设计时CTV 外扩PTV 边界的 大小提供参考。方法:选取30 例IMRT 的鼻咽癌患者,治疗过程中每周一次应用KV-CBCT 采集患者治疗前的CT 图像,将所得 图像与定位CT 图像进行匹配,分别测定X、Y、Z轴三个方向的摆位误差。结果:30 例患者共拍摄168 次KV-CBCT,获得168 组 摆位误差结果,群体摆位误差分别为X 轴-0.15± 1.43 mm,Y 轴0.20± 1.58 mm,Z轴-0.21± 1.65 mm;根据Van Herk 公式计算得 到各方向的CTV-PTV外放边界值X、Y、Z轴分别为3.1 mm、3.3 mm和3.4 mm。结论:应用KV-CBCT 影像系统可实时测量摆位 误差并在线进行纠正,减小摆位误差,为CTV-PTV外放边界提供参考。
英文摘要:
      Objective:To analyze the setup errors by KV-CBCT in nasopharyngeal carcinoma treated with Intensity Modulated Radiotherapy to provide the reference for calculate safety margins of PTV with CTV.Methods:30 patients with nasopharyngeal carcinoma who had received kilovoltage cone-beam computed tomography (KV-CBCT) and treated with IMRT were selected. The acquired images of KV-CBCT were compared to establish CT images with calculated setup errors of X-axis, Y-axis and Z-axis.Results:All the patients received the 168 KV-CBCT scans. The overall setup errors were below -0.15± 1.43 mm in X-axis, 0.20± 1.58 mm in Y-axis and -0.21± 1.65 mm in Z-axis; The margins required for CTV-PTV were calculated 3.1 mm, 3.3 mm and 3.4 mm, respectively, according to the Van Herk formula.Conclusion:The application of KV-CBCT imaging system on the margin of CTV-PTV can measure and reduce the setup errors by correcting online.
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