| 陈超 毕良佳 孟培松 刘玉三 苏鑫 代佳音.芦荟多糖含量测定及芦荟膏体外透皮吸收的实验研究[J].,2015,15(9):1647-1650 |
| 芦荟多糖含量测定及芦荟膏体外透皮吸收的实验研究 |
| Content in Aloe Polysaccharide fromAloe Barbadensis Miller andTransdermal Absorption of Aloe Mastic |
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| DOI： |
| 中文关键词: 芦荟多糖 库拉索芦荟 芦荟膏 透皮吸收 |
| 英文关键词: Aloe polysaccharide Aloe barbadensis miller Aloe mastic Transdermdelivery |
| 基金项目: |
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| 中文摘要: |
| 目的：研究芦荟膏中各功能成分体外透皮吸收的能力。方法：以Wistar大鼠的背部皮肤为透皮实验原料，每隔一定时间通过
分光光度法和高效液相色谱法测定透皮后接收池内芦荟多糖及蒽醌类含量。结果：随着芦荟膏剂量的增加，渗透量逐渐增加，芦
荟膏中芦荟多糖、芦荟大黄素、芦荟苷的渗透量随时间延长逐渐增加，但是渗透速率逐渐降低。结论：芦荟膏有较强的体外透皮吸
收能力，芦荟膏经皮给药能充分发挥其作用。 |
| 英文摘要: |
| Objective:To investiagte the invitro transdermal absorption ability.Methods:Back skin of Wista rats were used as the
transdermal experiment material. After transdermal absorption, the contents of aloe polysaccharide and anthraquinones in the reception
tank were measured at regular intervals by spectrophotometry and HPLC respectively.Results:With increasing doses of aloe mastic, the
amount of infiltration gradually increased.Permeability of aloe polysaccharide, aloe emodin, aloe extract aloin content increased
gradually, while the penetration rate decreased.Conclusion:Aloe mastic has a strong ability of invitro transdermal absorption , transderm
delivery of aloe mastic could make full use of its function. |
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