| 高有淑 陈代徒 郑燕 颜崇平 马步云.颈部血管超声检查粥样斑块对预防缺血性脑梗死的意义[J].,2015,15(23):4521-4524 |
| 颈部血管超声检查粥样斑块对预防缺血性脑梗死的意义 |
| Significance of Ultrasonography in Cervical Vascular Atherosclerosis Plaquein Prevention of Ischemic Cerebral Infarction |
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| DOI： |
| 中文关键词: 颈部血管 超声检查 粥样斑块 缺血性脑梗死 预防 |
| 英文关键词: Cervical vascular Ultrasonography Atherosclerotic plaque Cerebral infarction Prevention |
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| 中文摘要: |
| 目的：探讨颈部血管超声检查粥样斑块对预防缺血性脑梗死的意义。方法：对我院2012 年1月-2014 年1 月收治的40 例缺
血性脑梗死患者（观察组）进行回顾性分析，并同期选择来我院进行体检的正常志愿者40 例（对照组），对两组患者实施颈部血管
超声检查，并对比分析血清同型半胱氨酸（Hcy）和超敏C 反应蛋白（hs-CRP）水平。结果：观察组颈部动脉软斑、扁平斑、溃疡斑检
出率显著高于对照组，差异有统计学意义（P＜0.05）；两组硬斑检出率比较无统计学差异（P>0.05）。观察组颈总动脉内径和颈内动
脉颅外段内径显著窄于对照组，差异有统计学意义（P＜0.05）。研究组治疗后恢复良好24 例，恢复不良16 例，恢复良好组治疗前
颈动脉中层内膜厚度（IMT）显著低于恢复不良组（P＜0.05），且两组血清Hcy和hs-CRP比较无统计学差异（P>0.05）。恢复良好组
治疗后IMT、血清Hcy和hs-CRP显著低于恢复不良组（P＜0.05）。结论：颈部血管内的粥样斑块与缺血性脑梗死的发生有密切关
系，定期对患者颈部血管的粥样斑块进行超声检查对预防缺血性脑梗死具有重要的意义。 |
| 英文摘要: |
| Objective:To explore the significance of ultrasonography in cervical vascular atherosclerosis plaque in the prevention
of ischemic cerebral infarction(ICI).Methods:A total of 40 patients with ICI (observation group), who were admitted to Dazhou Central
Hospital of Sichuan Province from January 2012 to January 2014, were retrospectively analyzed, and in the same period, 40 normal
volunteers (control group), who came to Dazhou Central Hospital of Sichuan Province for physical examination, were selected. The two
groups were detected by neck vascular ultrasound, and their serum homocysteine (Hcy) and high sensitivity C reactive protein (hs-CRP)
were comparatively analyzed.Results:The detection rates of soft plaque,flat plaque and ulcer plaque of observation group were
significantly higher than those of the control group, the difference was statistically significant (P<0.05), while there was no statistically
significant difference in the detection rate of hard plaque between the two groups (P>0.05). The common carotid artery diameter(CCAD)
and extracranial internal carotid artery diameter (EICAD) of the observation group were significantly narrower than those of the control
group, and the difference was statistically significant (P<0.05). In the observation group, after treatment, 24 cases recovered well and 16
cases were in poor recovery; before treatment, the carotid artery intima-media thickness (IMT) in the patients with good recovery was
significantly lower than that in the patients with poor recovery（P＜0.05）, and there was no statistical difference in the serum Hcy and
hs-CRP between them（P>0.05）; after treatment, the IMT, serum Hcy and hs-CRP in the patients with good recovery were significantly
lower than those in the patients with poor recovery（P＜0.05）.Conclusion:The atherosclerotic plaque in the cervical vessels is closely
related to the occurrence of ICI, so regular ultrasound examination of the atherosclerotic plaque in the cervical vessels of patients has
important significance to the prevention of ischemic cerebral infarction. |
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