| 张芳君 栾卫红 董雅萌 王奇博 李丽娜.地氯雷他定联合地塞米松鼓室内注射对分泌性中耳炎患者咽鼓管功能的影响[J].,2015,15(33):6528-6530 |
| 地氯雷他定联合地塞米松鼓室内注射对分泌性中耳炎患者咽鼓管功能的影响 |
| Effect of the Loratadine Combined with DexamethasoneIntratympanic Injection on the Function of Eustachian Tube in Patientwith Secretory Otitis Media |
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| DOI： |
| 中文关键词: 地氯雷他定 地塞米松 鼓室内注射 分泌性中耳炎 咽鼓管功能 |
| 英文关键词: Loratadine Intratympanic dexamethasone injection Secretory otitis media Eustachian tube function |
| 基金项目:国家自然科学基金青年基金项目(81100714) |
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| 中文摘要: |
| 目的：观察地氯雷他定联合地塞米松鼓室内注射治疗分泌性中耳炎的效果及对咽鼓管功能的影响。方法：选择我院2013 年
6 月-2014 年6 月收治的分泌性中耳炎患者116 例，随机分为两组，对照组采用地塞米松鼓室内注射治疗，观察组在此基础上加
服地氯雷他定。观察并比较两组临床疗效及咽鼓管功能的恢复情况。结果：治疗后，两组咽鼓管功能不良率较治疗前明显降低(P＜
0.05)，观察组咽鼓管功能恢复率高于对照组，观察组治疗前后气骨导差差值明显大于对照组(P＜0.05)，观察组在治疗后1 周及1
月的总有效率均高于对照组(P＜0.05)。结论：地氯雷他定联合地塞米松鼓室内注射可减少渗出和中耳积液潴留，有效改善分泌性
中耳炎患者的咽鼓管功能，促进听力恢复。 |
| 英文摘要: |
| Objective:To observe the effect of loratadine combined with intratympanic dexamethasone injection on the secretory
otitis media.Methods:116 patients with secretory otitis media who were treated in our hospital from June 2013 to June 2014 were
selected and randomly divided into two groups. The patients in the control group were treated with the intratympanic dexamethasone
injection, while the patients in the observation group were treated with the loratadine on the basis of dexamethasone intratympanic
injection. Then the clinical effects and the recovery of eustachian tube function in the two groups were observed and compared before
and after the treatment.Results:After the treatment, the dysfunction of eustachian tube rates in the two groups were significantly lower
than before (P<0.05). The recovery rate of eustachian tube function in the observation group was significantly higher than that of the
control group, and the air bone gap was higher than that of the control group (P<0.05). The total effective rates in the observation group
were higher than those of the control group on 1st week and 1st month after treatment (P<0.05).Conclusion:Loratadine combined with
dexamethasone intratympanic injection could reduce middle ear effusion retention, improve the inflammatory function of eustachian tube
of patients with secretory otitis media and promote the recovery of hearing. |
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