| 易星 邹游 戴梦源 肖伯奎 张建功 刘兴发 陶泽璋 陈始明.变压器噪声暴露对豚鼠应激、肝肾及免疫功能的影响[J].,2015,15(34):6610-6613 |
| 变压器噪声暴露对豚鼠应激、肝肾及免疫功能的影响 |
| Effects of Transformer Noise on Stress, Hepato-renal Function and ImmuneFunction in Guinea Pigs |
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| DOI： |
| 中文关键词: 变压器噪声 豚鼠 应激 肝肾功能 免疫功能 |
| 英文关键词: Transformer noise Guinea Pigs Stress Hepato-renal function Immune function |
| 基金项目:国家电网公司总部科技项目（GY71-13-057） |
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| 中文摘要: |
| 目的：探讨短时间内变压器噪声暴露对豚鼠应激、肝肾及免疫功能的影响。方法：取32 只健康成年（5-6 月龄）豚鼠随机分为
实验组和对照组，每组16 只。实验组给予录制的变压器噪声（声压级范围40.8-55 dB SPL，频谱范围150-2000 Hz）连续暴露28
天，10 小时/ 天（晚10 点到早上8 点），对照组在相同条件下饲养，无噪声暴露。噪声暴露结束后，对实验豚鼠的应激、肝肾及免疫
功能进行定量评估比较。结果：噪声暴露28 天后实验组豚鼠的应激状态指标（ACTH、血清皮质醇）与对照组比较差异无统计学
意义（P>0.05），主要肝肾功能指标与对照组比较差异无统计学意义（P>0.05），免疫相关指标（IgG、IgA、IgE、IL-1、IL-2）比较差异无
统计学意义（P>0.05）。结论：声压级范围为40.8-55 dB SPL、频谱范围为150~2000 Hz的变压器噪声连续暴露28 天（10 小时/ 天）
对成年豚鼠应激、肝肾及免疫功能无明显影响。 |
| 英文摘要: |
| Objective:To study the stress, hepato-renal function and immune function changes in Guinea pigs after a short period
exposed to transformer noise.Methods:32 guinea pigs were grouped randomly into noise group (n=16) and control group (n=16). The
noise group was exposed to the transformer noise (sound pressure level was 40.8~55 dB SPL, frequency content was 150~2000 Hz) for
consecutively 28 days (10 hours per day, 10:00 pm~8:00 am). The control group was housed to the same conditions without the
transformer noise. The indexes of stress reactions, hepato-renal function and immune function of the guinea pigs were determined and
compared between two groups after a 28 days' noise exposure.Results:Compared with the control group, ACTH and CORT in the noise
group were not markedly different (P>0.05), and no obvious difference (P>0.05) was found in the liver and renal functions either. And the
noise group showed no significant difference (P>0.05) in related immune indexes (IgG, IgA, IgE, IL-1, IL-2) from the control group.Conclusion:Exposure of the transformer noise (sound pressure level: 40.8~55 dB, frequency content: 150~2000 Hz) in 28 days (10
hours per day, 10:00 pm~8:00 am) does not cause the stress, hepato-renal function and immune function changes in Guinea pigs. |
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