| 蔡磊 李艳 肖书傲 刘书尚 刘震 杨学文 王文斌 郎建勇 靳雁.腔镜微创食管癌根治术治疗Siewert I型胃食管结合部鳞癌的短期疗效评估[J].,2015,15(34):6682-6685 |
| 腔镜微创食管癌根治术治疗Siewert I型胃食管结合部鳞癌的短期疗效评估 |
| The Short-TermEfficacy of Three-Field Minimally Invasive Esophagectomyin the treatment of Siewert Type I Esophago-gastric Junctional SquamousCarcinoma |
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| DOI： |
| 中文关键词: 腔镜微创食管癌根治术 Siewert I型胃食管结合部鳞癌 短期疗效 安全性 |
| 英文关键词: Minimally invasive esophagectomy Minimally invasive esophagectomy Short-termefficacy Safety |
| 基金项目:国家自然科学基金项目（81300301）；第四军医大学优秀文职人员培养基金项目；第四军医大学西京医院2014 年度助推计划 |
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| 中文摘要: |
| 目的：探讨腔镜微创食管癌根治术治疗Siewert I型胃食管结合部鳞癌患者的短期临床疗效及安全性。方法：选取我科2009
年1 月1 日至2012 年3 月1 日收治的Seiwert I型胃食管结合部鳞癌患者114 例，并将其随机分为开胸食管切除术组(59 例)和
腔镜微创食管切除术组(55 例)，评估并比较两组的短期临床疗效及并发症的发生情况。结果：微创食管切除术组患者术后生存质
量评分评分均显著高于开胸食管切除术组(P<0.05)，患者2 年生存率为83.6%(46/55)，高于开胸食管切除术组(47/59，79.7%)。此
外，微创食管切除术组肺部并发症(9.09%vs 28.81%)和声带麻痹(0%vs 15.25%)的发生率均显著低于开胸食管切除术组(P<0.05)。
结论：腔镜微创食管癌根治术可显著提高Siewert I型胃食管结合部鳞癌短期疗效。 |
| 英文摘要: |
| Objective:To evaluate the short-term efficacy and safety of three-field minimally invasive esophagectomy in the
treatment of Siewert type I esophago-gastric junctional squamous carcinoma.Methods:From January 1, 2009, to March 1, 2012, 114
consecutive patients with Siewert type I esophagogastric junctional suamous carcinoma were involved in this retrospective study. Patients
were randomly assigned by acomputer-generated randomization sequence to receive either three-incision open esophagectomy or
minimally invasive esophagectomy. Details concerning short-term efficacy and complications were collected and analyzed.Results:Totally, 59 patients were involved in the open esophagectomy group and 55 patients were involved in the minimally invasive
esophagectomy group. The incidence of pulmonary morbidity (9.09%versus 28.81%) and vocal cord paralysis (0%versus 15.25%) in the
minimally invasive group were significantly lower than those in the open esophagectomy group (P<0.05). Furthermore, the postoperative
quality of life in the minimally invasive esophagectomy group was better than that in the open esophagectomy group. The 2-year survival
rate was 83.6%in the minimally invasive esophagectomy group (46 of 55 patients) and 79.7%in the open esophagectomy group (47 of59
patients), no significant difference was observed (P>0.05).Conclusion:Minimally invasive esophagectomy could significantly improve
the short-termefficacy of patients with Siewert type I esophagogastric junctional suamous carcinoma. |
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