| 笪荣峰 赵丽云 李玉红 马凌葵 武桂云 曹勇.复方氨基酸对肝硬化患者肝功能及AFP、CA199和CEA水平的影响[J].,2016,16(10):1898-1900 |
| 复方氨基酸对肝硬化患者肝功能及AFP、CA199和CEA水平的影响 |
| Effect on Liver Function and AFP, CA199 and CEA Levels by Amino Acid inPatients with Liver Cirrhosis |
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| DOI： |
| 中文关键词: 复方氨基酸 肝硬化 肝功能 |
| 英文关键词: Amino acid Liver cirrhosis Liver function |
| 基金项目:湖北省自然科学基金资助课题（2003ABA193） |
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| 中文摘要: |
| 目的：探讨复方氨基酸对肝硬化患者肝功能以及甲胎蛋白(Alpha fetal protein, AFP)、糖类抗原19-9 (Carbohydrate antigen
19-9,CA199)、癌胚抗原(Cancer embryo antigen, CEA)水平影响。方法：选取我院消化科收治的肝硬化患者98 例，根据治疗方法的
不同分为两组。对照组予以常规保肝治疗，实验组在对照组的基础上予以复方氨基酸注射液治疗。比较两组患者治疗1周及2 周
后的肝功能以及AFP、CA199 及CEA 水平的变化情况。结果：与对照组比较，实验组的临床疗效较高（87.04%Vs 72.22%），(P＜
0.05)。与对照组比较，治疗一周后实验组ALT水平较低（195.37± 13.42 U/L Vs 154.72± 13.44 U/L）、AST 水平较低（323.41±
21.33 U/L Vs 233.55± 21.63 U/L），TB 水平较低（125.36± 4.26 U/L Vs 108.16± 6.45 U/L）(P＜0.05)，治疗两周后，实验组ALT水平
较低（124.28± 15.84 U/L Vs 78.53± 12.55U/L）、AST 水平较低（147.15± 13.56 U/L Vs 83.42± 20.88 U/L），TB 水平较低（92.82±
9.64 U/L Vs 56.32± 7.43）(P＜0.05)。结论：复方氨基酸能够影响肝硬化患者肝功能，改善患者的临床症状，提高临床疗效。 |
| 英文摘要: |
| Objective:To investigate the effect of amino acid on liver function and AFP, CA199 and CEA levels in patients with
liver cirrhosis.Methods:98 patients with liver cirrhosis fromour hospital were selected and divided into the control group were treated by
routine treatment and the experiment group were treated on the base of the control group with the Amino Acid Compound Injection. The
liver function, AFP, CA199 and CEA levels were compared in 1 weeks and 2 weeks after treatment.Results:Compared with the control
group, the clinical curative effect were higher (87.04% Vs 72.22%), (P＜0.05), the ALT level after treatment a week were lower
(195.37± 13.42 U/L Vs 154.72± 13.44 U/L), (P＜0.05), the AST level were lower (323.41± 21.33 U/L Vs 233.55± 21.63 U/L), (P＜
0.05), the TB level were lower (92.82± 9.64 U/L Vs 56.32± 7.43), (P＜0.05). Compared with the control group, the ALT level after
treatment a week were lower(124.28± 15.84 U/L Vs 78.53± 12.55 U/L), (P＜0.05), the AST level were lower (147.15± 13.56 U/L Vs
83.42± 20.88 U/L), (P＜0.05), the TB level were lower (92.82± 9.64 U/L Vs 56.32± 7.43), (P＜0.05).Conclusion:Compound amino
acids can affect the liver function and CA199, CEA and AFP levels in patients with liver cirrhosis, improve the clinical symptoms and
improve the clinical effect. |
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