| 白雪波 辛佳映 李彦东 顾传英 张富强 余志阳.右美托咪定对全麻胃肠手术患者血流动力学及苏醒期躁动的影响[J].,2016,16(20):3902-3904 |
| 右美托咪定对全麻胃肠手术患者血流动力学及苏醒期躁动的影响 |
| Effects of Dexmedetomidine on the Hemodynamics and Agitation of Patientswith Gastrointestinal Surgery |
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| DOI： |
| 中文关键词: 右美托咪定 胃肠手术 血流动力学 苏醒期躁动 |
| 英文关键词: Dexmedetomidine Gastrointestinal surgery Hemodynamics Agitation |
| 基金项目:山东省卫生厅基金项目(2009BB1DB5) |
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| 中文摘要: |
| 目的：探究右美托咪定（Dex）对全麻胃肠手术患者血流动力学及苏醒期躁动的影响。方法：选取2013 年5 月-2015 年5 月在
我院接受全麻胃肠手术患者93例作为研究对象，根据麻醉方法不同将所选患者分为研究组（52 例）和对照组（41 例）。研究组患
者给予全身麻醉联合右美托咪定持续泵入麻醉，对照组仅给予全身麻醉。观察并比较两组患者手术开始时（T1）、手术进行时（T2）
及手术结束时（T3）的平均动脉压（MAP）、心率（HR）、脉搏氧饱和度（SpO2）、呼吸频率（RR）以及睡眠障碍镇静评分（Ramsay 评
分）。结果：研究组患者在T1，T2及T3的HR，RR 及MAP值均显著低于对照组，差异具有统计学意义（P<0.05）；两组患者各时间
点SpO2比较，差异均无统计学意义（P>0.05）。研究组患者各时间点的血流动力学指标比较，差异无统计学意义（P>0.05）。研究组
患者Ramsay评分（2.81± 0.28）显著高于对照组（1.51± 0.41），差异具有统计学意义（P<0.05）；研究组不良反应发生率（5.77%）显
著低于对照组（29.27%），差异具有统计学意义（P<0.05）。结论：Dex 对全麻胃肠手术患者具有良好的镇静、镇痛效果，能够稳定患
者血流动力学，对苏醒期恢复影响较小，值得临床应用推广。 |
| 英文摘要: |
| Objective:To investigate the effects of dexmedetomidine (Dex) on the hemodynamics and agitation of patients with
gastrointestinal surgery.Methods:93 cases who had taken the gastrointestinal surgery in our hospital from May 2013 to May 2015 were
selected as the research subjects. According to the different anesthesia methods, the selected patients were divided into the study group
(52 cases) and the control group (41 cases). The patients in the study group were treated with the general anesthesia combined with
dexmedetomidine continuous infusion, while the patients in the control group were treated with general anesthesia. Then the mean
arterial pressure (MAP), heart rate (HR), pulse oxygen saturation (SpO2), respiratory rate (RR) and Ramsay score of patients at the
beginning (T1), the process (T2) and the end of the operation were observed and compared.Results:At T1, T2 and T3, the HR, RR and
MAP in the study group were lower than those of the control group, and the differences were statistically significant (P<0.05); There was
no statistically significant difference about the SpO2 in the two groups at different time points (P>0.05); There was no significant
difference in the hemodynamic parameters of the study group at each time point (P>0.05). The Ramsay score of the study group was
(2.81± 0.28), which was higher than (1.51± 0.41) in the control group, and the difference was statistically significant (P<0.05); The
incidence of complications in the study group was 5.77%, which was lower than 29.27% in the control group, and the difference was
statistically significant (P<0.05).Conclusion:DEX of general anesthesia in patients undergoing gastrointestinal surgery has good
sedative, analgesic effect, which can keep the hemodynamics stable and less affect the agitation, and it is worthy of clinical application. |
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