| 张康秦 梁斌 赵蕊 郑恒兴 谢小伟 袁吉利.不同浓度七氟烷对小儿麻醉后cTn I, CRP及补体影响研究[J].,2016,16(21):4134-4137 |
| 不同浓度七氟烷对小儿麻醉后cTn I, CRP及补体影响研究 |
| Effect of the Troponin I, C Reactive Protein and Complement Changes byDifferent Concentration Seven Isoflurane Combined with Propofol afterAnesthesia in Children* |
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| DOI： |
| 中文关键词: 七氟烷 丙泊酚 肌钙蛋白I C 反应蛋白 |
| 英文关键词: Seven isoflurane Propofol Troponin I C reactive protein |
| 基金项目:陕西省自然科学基金项目(2002C218) |
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| 中文摘要: |
| 目的：探究不同浓度七氟烷联合丙泊酚对小儿麻醉后肌钙蛋白I、C 反应蛋白以及补体水平影响。方法：收集我院60 例ASA
Ⅰ级拟行全麻手术患儿，随机分为A、B、C三组，每组20 例。A组给予2%浓度的七氟烷联合丙泊酚麻醉；B 组2.5%浓度的七氟烷
联合丙泊酚麻醉；C 组3%浓度的七氟烷联合丙泊酚麻醉。检测三组患儿苏醒时间、术后情况，肌钙蛋白Ｉ（cTn I）、C反应蛋白
（CRP）及补体C3、C4 水平。结果：A 组、B 组自主呼吸时间、气管导管拔管时间、解除监护时间较C 组相比时间明显较短（P<0.05）；
但A 组与B 组比较无统计学差异（P>0.05）；与A 组比，B 组与C 组术后肌钙蛋白Ｉ、CRP水平较低，C3、C4水平较高（P<0.05），但
B 组与C 组血清指标比较无统计学差异（P>0.05）。结论：2.5%浓度的七氟烷联合丙泊酚是诱导小儿全身麻醉中的最佳浓度。 |
| 英文摘要: |
| Objective:To investigate the effect of the troponin I, C reactive protein and complement changes by different concentration
seven isoflurane combined with propofol after anesthesia in children.Methods:60 children with ASA grade I underwent general
anesthesia surgery from our hospital were selected and randomly divided into the group A, group B and group C with 20 cases in each
group.The group A received 2% concentration of seven isoflurane combined with propofol anesthesia. The group B received 2.5% concentration
of seven isoflurane combined with propofol anesthesia. The group C received 3% concentration of seven isoflurane combined
with propofol anesthesia.The recovery time, postoperative conditions, the expression levels of cardiacI (cTnI), C reactive protein (CRP)
and complement C3, C4 level were compared.Results:Compared with group C, the breathing time, tracheal extubation time and release
time were shorter in group B and group A（P<0.05）, the results of group A and B were not statistically significant（P>0.05）. Compared
with group A,the Troponin I and CRP levels were lower and the C3, C4 levels were higher in the group B and group C（P<0.05）. The difference
of serumindex in group B and C was not statistical of serum index（P>0.05）Conclusion:Seven concentration of 2.5%sevoflurane
combined with propofol is the best concentration in the induction of general anesthesia in children. |
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