| 何旺 贾真 郝姝 张渭涛 姚孝礼.缬沙坦联合通心络胶囊对糖尿病心肌病患者血清肌钙蛋白及SOD水平的影响[J].,2016,16(26):5100-5102 |
| 缬沙坦联合通心络胶囊对糖尿病心肌病患者血清肌钙蛋白及SOD水平的影响 |
| Effect of Valsartan combined with Tongxinluo on Cardiac Troponin and SOD in Patients with Diabetic Cardiomyopathy |
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| DOI： |
| 中文关键词: 缬沙坦 通心络胶囊 糖尿病心肌病 cTn I SOD |
| 英文关键词: Valsartan Tongxinluo capsule Diabetic cardiomyopathy cTn I SOD |
| 基金项目:陕西省自然科学基金项目(2006C130) |
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| 中文摘要: |
| 目的：探讨缬沙坦联合通心络胶囊对糖尿病心肌病患者血清肌钙蛋白，SOD 及生活质量的影响。方法：收集我院就诊或住院
治疗的60 例糖尿病心肌病患者，随机分为实验组和对照组，每组30 例。对照组患者给予缬沙坦口服治疗，实验组患者在此基础
上给予通心络治疗。检测并比较两组患者治疗前后血清cTn I、生活质量、SOD、运动耐量的变化情况。结果：与治疗前相比，两组患
者治疗后血清cTn I和生活质量评分均下降，而SOD和运动耐量水平均升高，差异具有统计学意义（P<0.05）；与对照组相比，实验
组患者治疗后血清cTn I和生活质量评分较低，而SOD 和运动耐量水平较高，差异具有统计学意义（P<0.05）。结论：缬沙坦联合通
心络胶囊能够降低糖尿病心肌病患者cTn I、生活质量评分，升高其SOD 以及运动耐量水平，对临床具有指导意义。 |
| 英文摘要: |
| Objective:To investigate the effect of valsartan combined with Tongxinluo on the cTn I, SOD and life quality of
patients with diabetic cardiomyopathy.Methods:60 patients with diabetic cardiomyopathy who were treated in our hospital were selected
and randomly divided into the experimental group and the control group, with 30 cases in each group. The patients in the control group
were treated with valsartan, while the patients in the experimental group were treated with Tongxinluo besides the conventional methods.
Then the serumlevels of cTn I and SOD, and the quality of life and exercise levels were detected and compared between the two groups
before and after the treatment.Results:Compared with before treatment, the serumlevels of cTn I and the quality of life in the two groups
decreased after the treatment, and the SOD and exercise levels increased, and the differences were statistically significant (P<0.05);
Compared with the control group after treatment, the serumlevels of CTN I and the quality of life in the experimental group were lower,
and the SOD and exercise resistant levels were higher, and the differences were statistically significant (P<0.05).Conclusion:Valsartan
combined with Tong xinluo capsule can reduce the I cTn and quality of life, and increase the SOD and exercise tolerance in patients with
diabetic cardiomyopathy, which is of great clinical significance. |
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