| 张明石 李晓飞 张世华 李明军 刘劲睿 王德超.脑胶质瘤患者手术前后睾酮水平变化及临床意义[J].,2016,16(27):5327-5329 |
| 脑胶质瘤患者手术前后睾酮水平变化及临床意义 |
| Changes of Testosterone Levels before and after Operation in Patients withCerebral Glioma and Its Clinical Significance |
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| DOI： |
| 中文关键词: 脑胶质瘤 睾酮水平 临床意义 |
| 英文关键词: Brain glioma Testosterone levels Clinical significance |
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| 中文摘要: |
| 目的：研究脑胶质瘤患者手术前后睾酮水平变化，并分析其临床意义。方法：选取2010 年2 月到2015 年6月我院脑胶质瘤
患者80 例为研究组，并选择同期颅脑良性肿瘤患者80 例为对照组，两组均给予手术治疗，检测术前和术后3 天、术后1 周患者
睾酮水平。结果：研究组术后各病理类型睾酮水平较治疗前显著降低（P＜0.05），但不同病理类型之间睾酮水平比较无统计学意义
（P＞0.05）；研究组术前睾酮水平显著高于对照组，比较差异具有统计学意义（P＜0.05）；术后3 天、术后一周研究组睾酮水平与术
前比较显著降低，差异具有统计学意义（P＜0.05）；术后1 周研究组睾酮水平与术后3 天比较无统计学意义（P＞0.05）；对照组术
前和术后各时间睾酮水平比较无统计学意义（P＞0.05）。结论：脑胶质瘤患者会出现睾酮水平紊乱，当睾酮水平明显增高时应警惕
脑胶质瘤的可能性。 |
| 英文摘要: |
| Objective:To study the changes of testosterone levels before and after operation in patients with cerebral glioma, and
analyze its clinical significance.Methods:Selected 80 cases of patients with cerebral glioma in our hospital from February 2010 to June
2015 as the study group and selected 80 cases of patients with benign tumor in the same period as the control group, the two groups were
treated with operation, detected the testosterone levels before operation, 3 days and 1 weeks after operation.Results:The testosterone level
of in each pathological types of the study group were significantly reduced (P<0.05), but there was no significant difference of the
testosterone levels between different pathological types(P>0.05); The testosterone level of study group was significantly higher than control
group before operation, the difference was statistically significant(P<0.05); The testosterone levels of study group 3 days and 1 weeks
after operation were significantly lower than before operation, the differences were statistically significant(P<0.05); There were no significant
difference of the testosterone levels in study group between 3 days after operation and 1 week after operation (P>0.05); There were
no significant difference of the testosterone levels between before operation and different times after operation of study group(P>0.05).Conclusion:The testosterone levels in patients with cerebral glioma is disordered, when the testosterone levels is significantly rise,it
should be alert to the possibility of glioma. |
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