文章摘要
宁佩芳,陈立群,刘 君,孟 晓,李 墨,张 勇.卵巢囊性颗粒细胞瘤的临床病理学特征、诊断及鉴别诊断[J].,2017,17(1):152-154
卵巢囊性颗粒细胞瘤的临床病理学特征、诊断及鉴别诊断
Clinicopathologic Features, Diagnosis and Differential Diagnosis of Ovarian Cystic Granulosa Cell Tumor
投稿时间:2016-06-30  修订日期:2016-07-10
DOI:10.13241/j.cnki.pmb.2017.01.039
中文关键词: 卵巢  囊性颗粒细胞瘤  病理诊断
英文关键词: Ovary  Cystic granulosa cell tumor  Pathological diagnosis
基金项目:辽宁省科技攻关项目(2012225016)
作者单位E-mail
宁佩芳 辽宁省肿瘤医院病理科 辽宁 沈阳 110042 woydyz@163.com 
陈立群 辽宁省肿瘤医院病理科 辽宁 沈阳 110042  
刘 君 辽宁省肿瘤医院病理科 辽宁 沈阳 110042  
孟 晓 辽宁省肿瘤医院病理科 辽宁 沈阳 110042  
李 墨 辽宁省肿瘤医院病理科 辽宁 沈阳 110042  
张 勇 辽宁省肿瘤医院病理科 辽宁 沈阳 110042  
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中文摘要:
      摘要 目的:探讨卵巢囊性颗粒细胞瘤的临床病理学特征、诊断和鉴别诊断要点。方法:复习1例卵巢囊性颗粒细胞瘤患者的临床资料、肿物的大体以及镜下病理组织学特征、免疫组化染色特征。结果:患者左侧单房囊性颗粒细胞瘤,大小为14.6 cm×18.9 cm ×9.8 cm,囊壁厚薄不均一;镜下可见内壁由颗粒细胞组成,细胞层数不一,可见典型的Call-Exner小体;免疫组化染色可见α-in- hibin,Vimentin,CD99均阳性。结论:卵巢囊性颗粒细胞瘤可依据镜下发现不典型增生的颗粒细胞、典型的Call-Exner小体和核沟等特征性的组织形态学作出诊断。
英文摘要:
      ABSTRACT Objective: To explore the clinicopathologic features, diagnosis and differential diagnosis of ovarian cystic granulosa cell tumor. Methods: The clinical data of one case of ovarian cystic granulosa cell tumor were reviewed. And the gross and histological features of the tumor were studied. Results: The patient had a left-sided unilocular cystic granulosa cell tumor, with the size of 14.6 cm× 18.9 cm×9.8 cm and uneven thickness of capsule wall. Under the microscope, the wall was consisted of granule cell, and the cell layer was visible. The typical Call-Exner bodies were also found under the microscope. Immunohistochemical staining results indicated that the alpha - inhibin, vimentin and CD99 were positive. Conclusion: The cystic granule cell tumor of the ovary could be diagnosed on the base of the histological characteristics like microscopic finding of atypical proliferation of granulosa cells, typical Call-Exner bodies and nuclear grooves.
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