| 陈建梅 王秋霜 黄党生 张丽伟 王淑华 姬冬冬 郭家瑞.超声造影技术评价颈动脉粥样硬化斑块稳定性的临床研究[J].,2017,17(2):280-282 |
| 超声造影技术评价颈动脉粥样硬化斑块稳定性的临床研究 |
| Clinical Study on Evaluation of Carotid Atherosclerotic Plaque Stability byContrast-enhanced Ultrasound |
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| DOI： |
| 中文关键词: 超声造影技术 颈动脉粥样硬化斑块 稳定性 临床研究 |
| 英文关键词: Contrast-enhanced ultrasound technique Carotid atherosclerotic plaque Stability Clinical study |
| 基金项目:解放军总医院科技创新苗圃基金项目（14KMM26） |
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| 中文摘要: |
| 目的：探讨超声造影技术评价颈动脉粥样硬化斑块稳定性的临床价值，为动脉粥样硬化诊断准确性提供参考。方法：根据实
时超声造影检查的回声图像特点将该院53 例（59 个斑块）颈动脉粥样硬化斑块患者分为软斑组（24 个）、混合斑组（18 个）、硬斑
组（17 个），比较3 组的造影增强率、造影增强程度分级，并对各类型斑块的时间- 强度进行定量分析。结果：59 个斑块中有40 个
呈现不同程度的增强，增强率为67.80%，其中软斑组、混合斑组、硬斑组超声增强率分别为87.50%、72.22%、35.29%，差异具有统
计学意义（P<0.05）；造影增强程度Ⅰ 级和Ⅲ 级在三组间差异具有统计学意义（P<0.05），其中硬斑组造影增强程度Ⅰ级个数较软斑
组和混合斑组多，软斑组造影增强程度Ⅲ级个数较混合斑组和硬斑组多，差异均有统计学意义（P<0.05）；软斑组达峰时间、平均渡
越时间均低于混合斑组和硬斑组，斑块峰值强度高于混合斑组和硬斑组，混合斑组达峰时间、平均渡越时间均低于硬斑组，斑块
峰值强度高于硬斑组，差异均具有统计学意义（P<0.05）。结论：超声造影技术可无创性地通过造影增强实时反映出颈动脉粥样硬
化斑块内的新生血管情况，提供参数成像与定量分析，正确评价斑块的稳定性。 |
| 英文摘要: |
| Objective:To investigate the clinical value of evaluation of carotid atherosclerotic plaque stability by
contrast-enhanced ultrasound, and to provide a reference for atherosclerosis diagnostic accuracy.Methods:53 cases (59 patches)of
patients with carotid artery atherosclerotic plaque were divided into soft plaque group (24 patches), mixed plaque group (18 patches)and
hard plaque group(17 patches) according to the characteristics of real-time ultrasound echo image angiography, compared the the contrast
enhancement rate and enhancement degree between the 3 groups,and quantitative analysis of time-intensity for each type of patch.Results:40 of the 59 patches showed different degrees of enhancement and the enhancement rate was 67.80%. The ultrasound
enhancement rates of soft plaque group, mixed plaque group and hard plaque group were 87.50%,72.22% and 35.29% respectively,and
the difference was statistically significant (P<0.05); The I and III grade of contrast enhancement degree between the three groups was
statistically significant (P<0.05), the number of I grade of contrast enhancement degree in hard plaque group was more than the soft and
mixed plaque groups,the number of III grade of contrast enhancement degree in soft plaque group was more than the hard and mixed
plaque groups, the difference was statistically significant (P<0.05); The peak time, average transit time of soft plaque group were lower
than the mixed plaque group and hard plaque group, the plaque peak intensity is higher than the mixed plaque group and hard plaque
group, the peak time and average transit time of the mixed plaque group was lower than the hard plaque group, the plaque peak intensity
was higher than the hard plaque group, and the differences were statistically significant (P<0.05).Conclusion:The ultrasound contrast
technique can be used to reflect the new blood vessel of carotid atherosclerotic plaque in real time, and provide the parameter imaging
and quantitative analysis to evaluate the stability of plaque. |
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