| 冯雨来 张杰 代政学 王昕 冯大跃.维生素D与PTH 相关性研究进展[J].,2017,17(2):385-388 |
| 维生素D与PTH 相关性研究进展 |
| Relationship of Vitamin D and PTH |
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| DOI： |
| 中文关键词: 维生素D PTH 骨代谢 |
| 英文关键词: Vitamin D PTH Bone metabolism |
| 基金项目:全军医疗卫生保健基金项目（14BJZ43） |
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| 中文摘要: |
| 维生素D 是人体必需的一种脂溶性营养素，随着科学技术不断进步，维生素D 对人类健康的作用逐渐被发现。已有研究表
明，维生素D 不仅与多种骨代谢相关疾病有关，并与心血管疾病、代谢综合征、感染、肿瘤、自身免疫疾病等关系密切。在骨代谢方
面，维生素D 的缺乏可能会导致软骨病、佝偻病、骨质疏松症，甚至会导致急性跌倒事件的发生和骨折的形成，而甲状旁腺激素
（PTH）是骨代谢过程中的关键分子。本文综述了维生素D 代谢过程及维生素D 受体多样性及维生素D 与甲状旁腺激素（PTH）相
关性，以便有助于探究维生素D 与骨代谢之间的关系。 |
| 英文摘要: |
| Vitamin D is an essential fat-soluble nutrient, with science and technology advance, the role of vitamin D on human
health has gradually been founded. Studies have shown that vitamin D is not only related with a variety of bone metabolism related
diseases, but also cardiovascular disease, metabolic syndrome, infection, cancer, autoimmune diseases. In terms of bone metabolism, the
lack of vitamin D may cause osteomalacia, rickets, osteoporosis, and lead to the formation and occurrence of acute fractures fall events.
At the same time, parathyroid hormone (PTH) is a key molecule in the process of bone metabolism. This review summarized the
metabolismof vitamin D and diversity of vitamin D receptor, and explores the relationship of Vitamin D and parathyroid hormone (PTH)
to explore the relationship between vitamin D and bone metabolism. |
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