| 马志宏,贾顺莲,高新英,王玉英,黄振兴.血液透析与腹膜透析对终末期糖尿病肾病患者预后的影响[J].,2017,17(34):6749-6751 |
| 血液透析与腹膜透析对终末期糖尿病肾病患者预后的影响 |
| Effect of Hemodialysis and Peritoneal Dialysis on the Prognosis of Patients with End-stage Diabetic Nephropathy |
| 投稿时间：2017-08-04 修订日期：2017-08-25 |
| DOI：10.13241/j.cnki.pmb.2017.34.032 |
| 中文关键词: 血液透析 腹膜透析 终末期糖尿病肾病 预后情况 |
| 英文关键词: Hemodialysis Peritoneal dialysis End stage diabetic nephropathy Prognosis |
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| 中文摘要: |
| 摘要 目的：对比分析血液透析与腹膜透析对终末期糖尿病肾病患者预后情况的影响。方法：选择2011年1月～2016年10月在我院进行诊治的终末期糖尿病肾病患者100例，随机分为血液透析组以及腹膜透组，每组各50例。分别给予血液透析治疗以及腹膜透治疗，比较两组患者透析前后的舒张压、收缩压、血红蛋白、血白蛋白、血磷、免疫反应性甲状旁腺激素以及血钙水平，观察患者的2年生存情况、3年生存情况以及死亡原因。结果：两组透析前后的舒张压、收缩压、血红蛋白、血磷、免疫反应性甲状旁腺激素以及血钙水平相比均无明显差异(P>0.05)，且两组间相比无明显差异(P>0.05)，血液透析组透析后的血白蛋白水平明显高于透析前(P<0.05)，且血液透析组透析后的血白蛋白水平明显高于腹膜透析组(P<0.05)；血液透析组存活2 年者33例，存活3 年者 26例；腹膜透析组存活 2 年者32例，存活 3 年者 25例。两组患者之间相比无明显差异(P>0.05)。两组患者的死亡原因主要包括包括多器官功能衰竭、心力衰竭、脑出血、重度感染以及休克等。结论：血液透析以及腹膜透析均为治疗终末期糖尿病肾病的有效方法，且二者对终末期糖尿病肾病患者预后情况的影响无明显差异，可根据患者的具体情况选用合适的透析治疗方法。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical effect of hemodialysis and peritoneal dialysis on the prognosis of patients with end-stage diabetic nephropathy. Methods: Selected 100 cases of patients with end-stage diabetic nephropathywho were treated in our hospital from January 2016 toDecember 2016, divided into two groups randomly, treated with hemodialysis and peritoneal dialysis.The diastolic blood pressure, systolic blood pressure, hemoglobin, serum albumin, serum phosphorus, immunoreactive parathyroid hormone and calcium level in two groups were compared before and after dialysis, observed in patients with 2 year survival, survival of 3 years and the cause of death. Results: There was no significant difference in diastolic blood pressure, systolic blood pressure, hemoglobin, serum phosphorus, immunoreactive parathyroid hormone and serum calcium levels between the two groups (P>0.05), and there was no significant difference between the two groups (P>0.05); the level of serum albumin in hemodialysis group was significantly higher than that before hemodialysis (P<0.05), and the serum albumin level in hemodialysis group was significantly higher than that in peritoneal dialysis group (P<0.05); In hemodialysis group, 33 cases survived for about 2 years, and there were no more than 3 years in the study group. The patients in the peritoneal dialysis group survived for 2 years, and the survival rate of the patients in the treatment group was 32 cases, and the survival rate of the patients in the treatment group was 25 years, with a survival rate of 3 years. There was no significant difference between the two groups (P>0.05). The main causes of death in the two groups included multiple organ failure, heart failure, severe infection and shock. Conclusion: Hemodialysis and peritoneal dialysis are effective methods for the treatment of end-stage diabetic nephropathy, there were no significant differences between the two and the prognosis of patients with end-stage diabetic nephropathy, can choose appropriate methods of dialysis treatment according to the specific circumstances of patients. |
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