| 李卫勤,邢永军,杨智泉,党培业,李耀章,马 琼,王彦东.金天格在老年骨质疏松性椎体骨折术后的应用及临床分析[J].,2018,(6):1116-1119 |
| 金天格在老年骨质疏松性椎体骨折术后的应用及临床分析 |
| Application of Jintian'ge in Treatment of Vertebral Compression Fracture after Operation in Senile Osteoporosis Patients |
| 投稿时间：2017-05-28 修订日期：2017-06-23 |
| DOI：10.13241/j.cnki.pmb.2018.06.024 |
| 中文关键词: 金天格 椎体骨折 骨质疏松 |
| 英文关键词: Jintian'ge Vertebral compression fracture Osteoporosis |
| 基金项目:国家自然科学基金项目(81201633) |
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| 中文摘要: |
| 摘要 目的：探讨和分析金天格胶囊在老年骨质疏松症导致的椎体骨折术后的作用和临床疗效。方法：将2013.01-2015.01来我院明确诊断为骨质疏松症导致的椎体骨折共计136人经纳入标准和排除标准筛选后，使用随机数字表将其随机分为2组。实验组给予经皮椎体成形术（PVP）+钙剂+维生素D+唑来磷酸+金天格胶囊治疗。对照组则不给予金天格进行治疗。所有患者均至少接受了12个月的系统随访观察。观察和进行比较的指标主要为疼痛（VAS），骨密度， Macnab腰椎功能评分以及血液肝肾功等指标。结果：在术后3月和12个月，两组患者在疼痛、骨密度及腰椎功能评分等方面较术前均有显著改善(P<0.05)。两组之间在上述指标中有统计学显著性差异。而在血液肝肾功等指标的比较中，则未发现疼显著统计学差异(P>0.05)。结论：金天格胶囊在骨质疏松性椎体骨折术后的应用，能够有效地提高治疗效果，安全程度较高，在临床中可进一步的进行推广应用。 |
| 英文摘要: |
| ABSTRACT Objective: To study the clinical application of Jintian'ge capsule in treatment of vertebral compression fracture after operation in senile osteoporosis patients. Methods: In this study, 136 senile osteoporotic vertebral compression fracture patients hospitalized in our hospital between 2013.01 and 2015.01 were selected and randomly divided into the control group and the treatment group. Patients in the control group were treated by PVP+ anti osteoporosis treatment, while those in the treatment group were given Jintian'ge capsule in addition to those. All patients received at least 12 months fellow up. Clinical outcomes were evaluated by VAS, bone density, lumbar vertebral function and hepatic and renal function test. Results: The VAS score, bone density and lumbar function of the patients were significantly better than pre-operation, and there was significantly difference between two groups too (P<0.05). There was no difference between two groups in the hepatic and renal function test and the complication. Conclusion: Jintian'ge capsule is applicable in adjuvant therapy after the osteoporotic vertebral compression facture after PVP surgery. |
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