| 曹高镇,汪 润,吴 旻,赵春婷,林庆陕.HFpEF、HFmrEF和HFrEF的临床特征及左心室重塑对比分析[J].,2018,(17):3269-3273 |
| HFpEF、HFmrEF和HFrEF的临床特征及左心室重塑对比分析 |
| Comparison of the Clinical Features and Left Ventricular Remodeling in Patients with HFpEF, HFmrEF and HFrEF |
| 投稿时间：2018-03-22 修订日期：2018-04-18 |
| DOI：10.13241/j.cnki.pmb.2018.17.014 |
| 中文关键词: 心力衰竭 左室射血分数 临床特征 左心室重塑 |
| 英文关键词: Heart failure Left ventricular ejection fraction Clinical feature Left ventricular remodeling |
| 基金项目:深圳市知识创新计划基础研究项目(JCYJ20150331142757380) |
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| 中文摘要: |
| 摘要 目的：探讨射血分数保留的心衰(HFpEF)、射血分数中间范围的心衰(HFmrEF)和射血分数下降的心衰(HFrEF)患者临床特征及左心室重塑的差别。方法：选取2013年2月1 日至2016年12月31日在我院心内住院的308名心力衰竭患者作为研究对象，根据入院后首次心脏彩超结果，按左室射血分数(LVEF)将入选的心力衰竭患者分为HFrEF组、HFmrEF组和HFpEF组，回顾性分析所有患者的临床一般资料、化验结果、超声数据和用药情况，对比分析3组患者的临床特征及左心室重塑的差别。结果：HFpEF 组为123例(39.9%)，HFmrEF组为98例(31.5%)，HFrEF组为88例(28.6%)；其中HFpEF组女性比例高于HFrEF组(59.4% vs. 38.6%，P<0.05)，高血压和房颤患病率HFpEF组高于HFrEF组(P<0.05)；HFpEF组左心室重构类型以向心性重塑为主，HFrEF组则以离心性重塑为主；HFmrEF组女性比例及高血压、房颤患病率等临床特征及左心室重塑类型分布则介于HFpEF组与HFrEF之间。结论：HFpEF，HFmrEF与HFrEF组患者临床特点及左心室重塑类型分布显著不同,应对不同左室射血分数的心力衰竭患者采取更有针对性的治疗措施。 |
| 英文摘要: |
| ABSTRACT Objective: To observe differences of clinical features and left ventricular remodeling in patients with heart failure with preserved ejection fraction (HFpEF), heart failure with mid-range ejection fraction (HFmrEF) and heart failure with reduced ejection frac- tion (HFrEF). Methods: A retrospective study was carried out and we employed medical records of 308 patients, admitted as a result of HF to the Hong Kong University-Shenzhen Hospital in the period between February 01, 2013 and December 31, 2016 due to HF. Results: 1). Of the 308 patients who were admitted due to HF, 123(39.9%) patients met the HFpEF criteria with 31.5% HFmrEF and 28.6% HFrEF. Comparing to HFrEF, HFpEF patients were tend to be more women (59.4%vs.38.6%, P<0.05), more hypertension and atrial fib- rillation. 2). More left ventricular concentric remolding cases were detected in HFpEF patients while more left ventricular eccentric re- molding cases were detected in HFrEF patients. 3). Clinical characteristics and left ventricular remolding types of HFmrEF fall in range between HFpEF and HFrEF. Conclusion: Different clinical characteristics and left ventricular remolding types were found in HFpEF,HFmrEF and HFrEF patients. |
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