| 陈 丽,刘书林,杨 茹,周 围,卓开敏.膝骨关节炎患者磁共振成像骨髓病变的检出率及其影响因素分析[J].,2019,19(2):295-299 |
| 膝骨关节炎患者磁共振成像骨髓病变的检出率及其影响因素分析 |
| Analysis of Detection Rate of Bone Marrow Lesions with MRI and Its Influence Factors in Patients with Knee Osteoarthritis |
| 投稿时间：2018-05-14 修订日期：2018-06-08 |
| DOI：10.13241/j.cnki.pmb.2019.02.020 |
| 中文关键词: 膝骨关节炎 磁共振成像 骨髓病变 检出率 影响因素 |
| 英文关键词: Knee osteoarthritis Magnetic resonance imaging Bone marrow lesion Detection rate Influence factor |
| 基金项目:四川省卫生厅科研基金资助项目（121056） |
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| 中文摘要: |
| 摘要 目的：研究膝骨关节炎（KOA）患者磁共振成像（MRI）骨髓病变（BML）的检出率及其影响因素。方法：选择从2015年1月到2017年12月在我院接受诊治的KOA患者182例进行研究。对患者实施MRI诊断，统计KOA患者BML的检出率及病变发生位置，并应用单因素分析和Logistic回归分析KOA患者发生BML的影响因素。结果：182例KOA患者共检出92例BML，检出率为50.55%。其中BML发生在外侧股骨、内侧股骨以及外侧胫骨、内侧胫骨的构成比均超过22.00%，检出率均超过11.00%。单因素分析显示，KOA患者发生BML与年龄、体质量指数（BMI）、病程、吸烟频率及饮酒频率等因素有关（P<0.05）。根据Logistic回归分析可知，KOA患者发生BML的影响因素主要包括年龄≥60岁、BMI≥24 kg/m2、病程≥5年、吸烟频率≥10支/d以及饮酒频率≥4次/周（P<0.05）。结论：KOA患者BML检出率较高，且影响BML发病的因素较多，临床上可从患者的年龄、BMI、病程、吸烟频率以及饮酒频率等方面进行考察，从而有助于患者病情进展的评估和后续诊治工作的进行。 |
| 英文摘要: |
| ABSTRACT Objective: To study the detection rate of bone marrow lesion (BML) with magnetic resonance imaging (MRI) and its influence factors in patients with knee osteoarthritis (KOA). Methods: A total of 182 patients with KOA, who were treated in First Affili- ated Hospital of Chengdu Medical College from January 2015 to December 2017, were selected and were detected with MRI. The detec- tion rate and location of BML in the patients with KOA were statistically analyzed. Single factor analysis and Logistic regression analysis were used to evaluate the influence factors of BML in the patients with KOA. Results: Among 182 patients with KOA,92 patients had BML, and the detection rate was 50.55%, in which, the constituent ratio of BML in lateral femur, medial femur, lateral tibia and medial tibia was more than 22.00%, the detection rate was higher than 11.00%. Single factor analysis showed that the incidence of BML in the patients with KOA was related to age, body mass index(BMI), course of disease, smoking frequency and drinking frequency(P<0.05). According to Logistic regression analysis, the main influence factors of BML in the patients with KOA were age≥60 years old, BMI≥24 kg/m2, course of disease≥5 years, smoking frequency≥10 pieces/d and drinking frequency≥4 times/week(P<0.05). Conclusion: KOA patients have higher detection rate of BML, and there are many factors affecting the incidence of BML. It should be investigated from the aspects of age, BMI, course of disease, smoking frequency and drinking frequency, which is helpful for the evaluation of pa- tients' progress and subsequent diagnosis and treatment. |
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