| 张佑民,尚 曦,林德重,李杨杨,赵志军.单向纳入式人工胃底活瓣在食管-胃胸内吻合抗返流中的应用研究[J].,2019,19(6):1119-1121 |
| 单向纳入式人工胃底活瓣在食管-胃胸内吻合抗返流中的应用研究 |
| Application of One-way Inclusion Artificial Gastric Foot Valve for the Anti-reflux of Esophago-gastric Anastomosis |
| 投稿时间：2018-08-20 修订日期：2018-09-16 |
| DOI：10.13241/j.cnki.pmb.2019.06.025 |
| 中文关键词: 单向纳入式人工胃底活瓣 食管中下段癌根治术 返流症状 生活质量 食管-胃胸内吻合 |
| 英文关键词: One-way integrated artificial gastric fundus valve Esophageal mid-lower cancer radical surgery Reflux symptoms Quality of life Esophageal-gastric anastomosis |
| 基金项目:国家自然科学基金项目(81441082) |
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| 中文摘要: |
| 摘要 目的：探讨单向纳入式人工胃底活瓣用于食管-胃胸内吻合抗返流患者的临床效果。方法：选择2017年3月-2018年3月入院治疗的食管中下段癌根治术患者70例，所有患者均在腹腔镜下完成全胸腹腔镜下食管-胃胸内吻合手术，术后采用胃肠吻合器完成食管胃右胸内吻合完成消化道重建。根据抗返流方法分为对照组(n=35例)和观察组(n=35例)。对照组术后包埋吻合口，观察组术后采用单向纳入式人工胃底活瓣，两组治疗完毕后对患者效果进行评估。记录并比较两组治疗后痊愈、全身衰竭死亡、吻合口瘘、返酸及吐苦水返流症状、烧心感的发生率；采用WHOQol-BREF生活量表对两组治疗前、治疗后生活质量进行比较。结果：观察组治疗后痊愈率显著高于对照组(71.43% vs. 42.86%，P<0.05)，全身衰竭死亡、吻合口瘘、返酸及吐苦水返流症状、烧心感发生率均明显低于对照组(P<0.05)。两组治疗后生理健康、心理状态、社会关系、周围环境及独立能力评分均显著高于治疗前(P<0.05)，且观察组治疗后生理健康、心理状态、社会关系、周围环境及独立能力评分均高于对照组(P<0.05)。结论：单向纳入式人工胃底活瓣用于食管中下段癌根治术患者能降低返流症状的发生率，能提高患者生活质量。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical effect of one-way artificial gastric fundus valve Utend on the patients with anti-reflux in the esophagogastric anastomosis. Methods: A total of 70 patients undergoing radical esophageal cancer from March 2017 to March 1818 were selected. All the patients underwent laparoscopic laparoscopic esophageal and intragastric anastomosis. Intestinal stapler completed esophagogastric right intrathoracic anastomosis was performed to complete the reconstruction of the digestive tract. According to the anti-reflux method, they were divided into the control group (n=35 cases) and the observation group (n=35 cases). In the control group, the anastomosis was not included in the postoperative period, and in the observation group, the one-way integrated artificial gastric fundus valve was used after the operation. The effect of the patient after the treatment was evaluated in both groups. Record and count the two groups recovered after compare, death due to systemic failure, anastomotic leakage, acid reflux, diarrhea reflux symptoms, and heartburn sensation; WHOQol-BREF life scale was used to evaluate the quality of life before and after treatment in both groups. The incidence of reflux and the impact on quality of life were compared between two groups.Results: The recovery rate of observation group after treatment was higher than that of the control group (71.43% vs. 42.86%, P<0.05). The death rate of systemic failure, anastomotic leakage, acid reflux, diarrhea and diarrhea reflux symptoms, and burning heart sensation were lower in the observation group than those in the control group(P<0.05). The physical health, mental status, social relationship, surrounding environment and independent ability scores of observation group and the control group after treatment were all higher than those before treatment (P<0.05); the observation group received physical health and psychological state after treatment. The scores of social relations, surrounding environment and independent ability were higher than those in the control group (P<0.05). Conclusion: One-way integrated artificial gastric fundus flap can be used to reduce the incidence of reflux symptoms in patients with esophageal mid-lower cancer radical resection, and improve the quality of life of patients. |
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