| 王利民,刘善凤,阿腾古丽,王若溪,王 平.湖北地区健康成人网织红细胞相关参数参考区间的建立[J].,2019,19(15):2877-2879 |
| 湖北地区健康成人网织红细胞相关参数参考区间的建立 |
| Establishment of Reference Interval for Reticulocyte Related Parameters in Healthy Adults in Wuhan |
| 投稿时间：2018-11-24 修订日期：2018-12-19 |
| DOI：10.13241/j.cnki.pmb.2019.15.016 |
| 中文关键词: 网织红细胞 BC-6800血液分析仪 参考区间 建立 |
| 英文关键词: Reticulocyte BC-6800 automatic blood analysis instrument Reference interval Establish |
| 基金项目:湖北省自然科学基金项目（2014CBK329） |
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| 中文摘要: |
| 摘要 目的：建立湖北地区健康成人网织红细胞相关参数的参考区间，以便更准确为临床提供服务。方法：选取我院体检中心751例健康体检者进行空腹静脉采血，采用迈瑞BC-6800血液分析仪进行网织红细胞相关参数检测，建立网织红细胞百分比（RET%）、网织红细胞绝对值（RET#）、低荧光网织红细胞百分比（LFR%）、中荧光网织红细胞百分比（MFR%）、高荧光网织红细胞百分比（HFR%）和幼稚网织红细胞百分比（IFR%）的参考区间。结果：RET%、RET#、LFR%、MFR%、HFR%和IFR%均呈非正态分布，建立的参考区间分别为：RET%：0.54~1.80 ；RET#：男0.029~0.098、女0.024~0.093；LFR%：男89.9~98.7、女92.4~98.8；MFR%：男1.3~9.6、女1.2~7.3；HFR%：男0~0.5、女0~0.1；IFR%：男1.3~10.3、女1.2~7.4。健康成人男性LFR%、MFR%、IFR%结果存在年龄组间显著性差异，女性未发现年龄组间存在差异性。结论：湖北地区健康成人网织红细胞6项相关参数的参考区间存在地区特异性、性别差异性以及年龄差异性。不同地区实验室应根据当地调查情况，适当的调整网织红细胞相关参数的参考区间，以便更准确的为临床提供判断标准。 |
| 英文摘要: |
| ABSTRACT Objective: Objective to establish a reference interval for reticulocyte parameters in healthy adults in Hubei, so as to provide more accurate clinical services. Methods: 751 healthy adults from medical examination center in our hospital were selected to collect blood by fasting vein, and the related parameters of reticulocyte were detected by BC-6800 automatic blood analysis instrument, and the reference interval of RET%, RET#, LFR%, MFR%, HFR% and IFR% was established. Results: RET%, RET#, LFR%, MFR%, HFR% and IFR% were distributed in non normal distribution, and the reference intervals were RET%: 0.54~1.80; RET#: male 0.029~0.098, female 0.024~0.093; LFR%: male 89.9~98.7, female 92.4~98.8; MFR%: male 1.3~9.6, female 1.2~7.3; HFR%: male 0~0.5, female 0~0.1; IFR%: male 1.3~10.3, female 1.2~7.4. There were significant differences in age, LFR%, MFR% and IFR% among healthy man. There was no difference in age among women. Conclusion: The reference interval of 6 parameters related to reticulocyte in healthy adults in Hubei area has regional specificity, sex difference and age difference. Different regional laboratories should adjust the reference interval of reticulocyte related parameters according to the local investigation, so as to provide more accurate criteria for clinical judgment. |
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