| 张 磊,许家莹,荣 慧,时燕萍,季 静.化瘀消癥剂多途径联合治疗慢性盆腔痛的临床研究[J].,2019,19(19):3708-3711 |
| 化瘀消癥剂多途径联合治疗慢性盆腔痛的临床研究 |
| A Clinical Study on the Hua Yu Xiao-zheng Formula in Multi-way Combination Therapy in the Treatment of Chronic Pelvic Pain |
| 投稿时间：2019-04-07 修订日期：2019-04-28 |
| DOI：10.13241/j.cnki.pmb.2019.19.025 |
| 中文关键词: 化瘀消癥剂 口服、灌肠、穴位离子导入多途径联合疗法 慢性盆腔痛 |
| 英文关键词: Hua Yu Xiao-zheng Formula Multi-way combination therapy Chronic pelvic pain |
| 基金项目:江苏省中医药管理局科技项目(YB2015023) |
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| 中文摘要: |
| 摘要 目的：探讨化瘀消癥剂口服、灌肠联合穴位离子导入多途径联合疗法治疗慢性盆腔痛(子宫内膜异位症、慢性盆腔炎性疾病)的临床疗效。方法：将60例慢性盆腔痛患者随机分为2组，每组28例。治疗组患者采用化瘀消癥剂口服、灌肠联合穴位离子导入方法；对照组患者采用散结镇痛胶囊进行口服，排除月经周期连续用药20天当做1个疗程，治疗持续3个疗程。治疗后，比较两组患者的总有效率、治疗前后中医症候以及局部体征评分、糖类抗原125(CA125)水平的变化。结果：治疗后，治疗组总有效率显著高于对照组(89.28% vs. 57.14%，P＜0.05)。两组患者的局部体征评分、中医症候评分和总积分均比治疗前有一定程度下降(P<0.05)。两组患者治疗后的中医症候积分、总积分、体征积分均较治疗前明显降低，且治疗组以上指标均明显低于对照组(P＜0.05)。两种患者治疗后血清CA125水平均较治疗前明显降低(P＜0.05)，但两组间比较差异无统计学意义(P>0.05)。两组治疗期间不良反应的发生率对比差异无统计学意义（14.29% vs. 10.71%, P>0.05）。结论：通过口服、灌肠外加穴位离子导入三种途径联合给予化瘀消癥剂治疗慢性盆腔痛患者可以显著提高其临床效果，有效改善患者的盆腔疼痛程度、中医症候和局部体征，安全有效，值得临床应用。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical efficacy of Hua Yu Xiao-zheng Formula and enema combined with acupoint iontophoresis in the treatment of chronic pelvic pain (endometriosis, chronic pelvic inflammatory disease). Methods: Sixty patients with chronic pelvic pain were randomly divided into the two groups, 28 in each group. The patients in the treatment group were treated with Hua Yu Xiao-zheng Formula and Enema combined with acupoint iontophoresis. The control group was given orally administered with Sanjie Analgesic Capsules. Excluding the menstrual cycle for 20 days as a course of treatment, and the treatment lasted for 3 courses. After treatment, the total effective rate, the symptoms of TCM and local physical signs, and the changes of carbohydrate antigen 125 (CA125) levels were compared between the two groups. Results: After treatment, the total effective rate of the treatment group was significantly higher than that of the control group ((89.28% vs. 57.14%, P<0.05). The local physical scores, TCM symptom scores and total scores of the two groups were lower than before treatment(P<0.05). The TCM syndrome scores, total scores and physical scores of the two groups were significantly lower than those before treatment, and the above indexes of the treatment group were significantly lower than the control group(P<0.05). The CA125 level was significantly lower than that before treatment(P<0.05), but there was no significant difference between the two groups(P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (14.29% vs. 10.71%, P>0.05). Conclusion: Patients with chronic pelvic pain treated by oral administration, enema and acupoint iontophoresis in combination with Hua Yu Xiao-zheng Formula can significantly improve the clinical effect and effectively improve the patient's pelvic pain, TCM symptoms and local signs. Safe and effective, worthy of clinical application. |
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