| 曾秀利,曾 娟,侯国胜,郭林晗,张惠华,张东璐.油田工作人员高尿酸血症患病率调查及其影响因素分析[J].,2020,(6):1120-1123 |
| 油田工作人员高尿酸血症患病率调查及其影响因素分析 |
| Investigation on the Prevalence of Hyperuricemia in Oilfield Workers and Analyze Its Influencing Factors |
| 投稿时间：2019-10-07 修订日期：2019-10-30 |
| DOI：10.13241/j.cnki.pmb.2020.06.027 |
| 中文关键词: 高尿酸血症 油田工作人员 影响因素 患病率 |
| 英文关键词: Hyperuricemia Oilfield workers Influencing factors Prevalence |
| 基金项目:河北省医学科学研究基金项目（201702807）；华北油田分公司科技项目（2017HB-G07） |
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| 中文摘要: |
| 摘要 目的：了解油田工作人员高尿酸血症（HUA）患病率并分析其影响因素。方法：于2018年1月至2018年12月通过随机抽样法选取300例华北油田的工作人员。统计所有油田工作人员的HUA患病率，并根据HUA发生与否分成HUA组41例与非HUA组259例。采用单因素分析及多因素Logistic回归分析HUA的影响因素。结果：300例油田工作人员HUA患病率为13.67%（41/300），其中男性油田工作人员血清尿酸水平及HUA患病率均高于女性（均P＜0.05）。HUA组肥胖、饮酒、高血压、高血糖、高血脂症人数占比高于非HUA组（均P＜0.05）。HUA组尿素氮（BUN）、血肌酐（Scr）水平均高于非HUA组，而肾小球滤过率（eGFR）水平低于非HUA组（均P＜0.05）。多因素Logistic回归分析显示，男性、肥胖、饮酒、高血压、高血糖、高血脂症及BUN＞5.0 mmol/L、Scr＞130.0 μmol/L、eGFR＜130.0 mL/（min?1.73m2）均是油田工作人员HUA的独立危险因素（均P＜0.05）。结论：油田工作人员HUA患病率较高，应予以重视。男性、肥胖、饮酒、高血压、高血糖、高血脂症、BUN、Scr水平较高以及eGFR较低的人群HUA发生的风险较高，可通过针对上述因素予以干预，继而降低HUA的发生风险。 |
| 英文摘要: |
| ABSTRACT Objective: To understand the prevalence of hyperuricemia (HUA) in oilfield workers and analyze its influencing factors. Methods: 300 oilfield workers from Huabei oilfield from January 2018 to December 2018 were selected by random sampling method. The prevalence of HUA in all oilfield workers was counted. According to the occurrence of HUA, 41 cases were divided into HUA group and 259 cases into non-HUA group. Univariate analysis and multivariate Logistic regression were used to analyze the influencing factors of HUA. Results: The prevalence of HUA in 300 oilfield workers was 13.67% (41/300), and the serum uric acid level and HUA prevalence in male oilfield workers were higher than that in female (all P<0.05). The proportion of obesity, drinking, hypertension, hyperglycemia and hyperlipidemia in HUA group were higher than those in non-HUA group (all P<0.05). The blood usea nitrogen(BUN) and serum creatinine (Scr) level in HUA group were higher than those in non-HUA group, while the glomerular filtration rate (eGFR) level was lower than that in non-HUA group (all P<0.05). Multivariate Logistic regression analysis showed that male, obesity, drinking, hypertension, hyperglycemia, hyperlipidemia and BUN＞5.0 mmoL/L, Scr＞130.0 μol/L and eGFR＜130.0 mL/（min?1.73m2）were all independent risk factors for HUA in oilfield workers (all P<0.05). Conclusion: The prevalence of HUA in oilfield workers is high, which should be paid attention. Male, obesity, drinking, hypertension, hyperglycemia, hyperlipidemia, higher Scr levels, higher BUN levels and lower eGFR leves are at higher risk of HUA. These factors can be intervened to reduce the risk of HUA. |
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