文章摘要
腹腔镜手术对老年结肠癌患者的影响研究
Research on the effect of laparoscopic surgery on elderly patients with colon cancer
投稿时间:2021-04-28  修订日期:2021-04-28
DOI:
中文关键词: 结肠癌  老年患者  腹腔镜  疗效  安全性
英文关键词: Colon cancer  Elderly patients  Laparoscopy  Efficacy  Safety
基金项目:
作者单位邮编
余智涛* 广东省第二人民医院 510317
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中文摘要:
      目的 探讨腹腔镜手术对老年结肠癌患者的影响研究。方法 以我院2017年6月-2018年7月85例老年结肠癌手术患者为研究对象,根据患者手术方式不同分为A(43例)和B42例;A组给予开腹术,B组给予腹腔镜术;对比两组临床指标、血清炎症因子、免疫分子、并发症及预后。结果 B组术中出血量(83.26±25.47)、肛门排气时间(56.24±13.26)、淋巴结清扫时间(22.57±7.54)、住院时间(8.84±4.46)明显低于A组(129.36±49.31,79.41±22.15,23.32±8.46,11.36±5.78)(P<0.05)。术后1d,B组IL-6(6.54±1.02 ng/L)、CRP(31.87±5.74 mg/L)与A组(8.16±1.14 ng/L,50.84±7.63 mg/L)差异明显(P<0.05)。术后3个月,B组CD4+(44.28±5.23 %)、CD8+(35.27±4.58 %)与A组(40.03±5.72 %,30.24±4.26 %)差异明显(P<0.05)。B组(14.29%)并发症发生率明显低于A组(37.21%)(P<0.05)。两组生存与复发率无明显差异(P>0.05)。结论 腹腔镜手术可明显改善老年结肠癌患者临床指标、血清炎症因子、免疫分子水平,并降低患者并发症,且其生存率、复发率与开腹手术并无明显差异。
英文摘要:
      Objective To investigate the effect of laparoscopic surgery on elderly patients with colon cancer. Methods Taking 85 elderly colon cancer surgery patients in our hospital from June 2017 to July 2018 as the research object, according to the different surgical methods, 43 cases were divided into the A group and 42 cases the B group; The A group was given laparotomy, and the B group was given laparoscopy; The related indicators of the two groups were compared.Results The intraoperative blood loss (83.26±25.47) and anal exhaust time (56.24) of the B group ±13.26), lymph node dissection time (22.57±7.54), hospitalization time (8.84±4.46) compared with the A group (129.36±49.31, 79.41±22.15, 23.32±8.46, 11.36±5.78) were significantly lower (P<0.05). On the 1st day after operation, the IL-6 (6.54±1.02 ng/L), CRP (31.87±5.74 mg/L) in the B group compared with the A group (8.16±1.14 ng/L, 50.84±7.63 mg/L)were significant differences (P< 0.05). Three months after the operation, the CD4+ (44.28±5.23%), CD8+ (35.27±4.58%) in the B group compared with the A group (40.03±5.72%, 30.24±4.26%) were significant differences (P<0.05). The incidence of complications in the B group (14.29%) compared with the A group (37.21%)was significantly lower (P<0.05). The survival and recurrence rates between the two groups has no significant difference (P>0.05). Conclusion Laparoscopic surgery can significantly improve the clinical indicators, serum inflammatory factors, and immune molecular levels in elderly patients with colon cancer, and reduce the complications of patients, and there is no significant difference between the survival rate and recurrence rate and open surgery.
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