文章摘要
刘昌营,杜兴莉,高 峰,逄启然,赵 颖,逄明杰.鼻腔结构异常与慢性泪囊炎的关系及对手术预后的影响[J].,2021,(8):1550-1554
鼻腔结构异常与慢性泪囊炎的关系及对手术预后的影响
The Relationship between Abnormal Nasal Structure and Chronic Dacryocystitis and Its Effect on Surgical Prognosis
投稿时间:2020-10-04  修订日期:2020-10-27
DOI:10.13241/j.cnki.pmb.2021.08.033
中文关键词: 慢性泪囊炎  鼻腔结构异常  预后  影响因素
英文关键词: Chronic dacryocystitis  Abnormal nasal structure  Prognosis  Affecting factors
基金项目:山东省医药卫生科技发展计划项目(2018WS364);青岛市医疗卫生优秀人才培养项目(V市DTR2017y15);青岛市公共领域科技支撑计划项目[2012-1-3-1- (11) -nsh]
作者单位E-mail
刘昌营 青岛大学医学部临床医学系 山东 青岛 266071平邑县中医医院耳鼻喉科 山东 临沂 273300 liu_work999@sina.com 
杜兴莉 青岛大学附属青岛市市立医院耳鼻咽喉头颈外科 山东 青岛 266011  
高 峰 青岛大学附属青岛市市立医院耳鼻咽喉头颈外科 山东 青岛 266011  
逄启然 青岛大学附属青岛市市立医院耳鼻咽喉头颈外科 山东 青岛 266011  
赵 颖 青岛大学附属青岛市市立医院眼科 山东 青岛 266011  
逄明杰 青岛大学附属青岛市市立医院耳鼻咽喉头颈外科 山东 青岛 266011  
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中文摘要:
      摘要 目的:研究鼻腔结构异常与慢性泪囊炎(CD)的关系及对手术预后的影响。方法:将从2017年2月~2019年2月青岛大学附属青岛市市立医院收治的200例CD患者纳入研究,分析其鼻腔结构异常发生情况。将患者按照是否发生鼻腔结构异常分成异常组(n=132)及无异常组(n=68),比较两组各项基线资料,并分析CD患者鼻腔结构异常发生的影响因素。将所有患者按照术后疗效的差异分成治愈组(n=152)及未治愈组(n=48),并以多因素Logistic回归分析CD患者预后的影响因素。结果:200例患者共检出鼻腔结构异常132例,占比66.00%。异常组年龄<60岁、职业状态为待业以及有吸烟史人数占比均高于无异常组(均P<0.05)。经多因素Logistic回归分析发现:年龄<60岁、职业状态为待业以及有吸烟史均是CD患者鼻腔结构异常的危险因素(均P<0.05)。经单因素分析可得:年龄、鼻泪管引流管拔除时间以及鼻腔结构异常均和CD患者预后有关(均P<0.05)。经多因素Logistic回归分析发现:年龄≥60岁、鼻泪管引流管拔除时间>术后3个月以及鼻腔结构异常均是CD患者预后的危险因素(均P<0.05)。结论:鼻腔结构异常与CD发生、发展密切相关,且多见于年龄<60岁,有吸烟史以及待业人群中。此外,年龄≥60岁、鼻泪管引流管拔除时间在术后3个月以上以及鼻腔结构异常均是CD患者手术预后的独立危险因素,应予以重点关注。
英文摘要:
      ABSTRACT Objective: To study the relationship between abnormal nasal structure and chronic dacryocystitis (CD) and its effect on the prognosis of the operation. Methods: 200 CD patients admitted to Qingdao Municipal Hospital Affiliated to Qingdao University from February 2017 to February 2019 were included in the study, to analyze the occurrence of nasal structural abnormalities, which were divided into the abnormal group(n=132) and the non abnormal group(n=68) according to whether or not the nasal structural abnormalities occurred. The baseline data of the two groups were compared and the influencing factors of abnormal nasal structure in CD patients were analyzed. All patients were divided into cured group (n=152) and non cured group (n=48) according to the difference of postoperative curative effect. The influencing factors of prognosis of CD patients were analyzed by multivariate Logistic regression analysis. Results: 132 cases of abnormal nasal structure were detected in 200 patients, accounting for 66.00%. The abnormal group was younger than 60 years old, the occupational status was unemployed, and the proportion of people with smoking history was higher than that in the non abnormal group (all P<0.05). Through multivariate Logistic regression analysis, it was found that: age less than 60 years old, occupational status as unemployed, and history of smoking are risk factors for nasal structure abnormalities in CD patients (all P<0.05). According to single factor analysis, age, nasolacrimal drainage tube removal time and nasal structure abnormalities are all related to the prognosis of CD patients (all P<0.05). Multivariate Logistic regression analysis found that: age greater than or equal to 60 years old, nasolacrimal drainage tube removal time greater than 3 months after operation, and abnormal nasal structure are risk factors for the prognosis of CD patients (all P<0.05). Conclusion: Abnormal nasal structure is closely related to the occurrence and development of CD, and most of them are less than 60 years old, with a history of smoking and those who are not working. In addition, age less than 60 years, nasolacrimal drainage tube removal time more than 3 months after surgery, and abnormal nasal cavity structure are independent risk factors for the prognosis of patients with CD, and should be focused on.
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