| 林嘉欣,梁敏诗,黄晓萍,周映彬,任利容.穴位埋线联合补肾调经汤对多囊卵巢综合征患者性激素水平及代谢指标的影响[J].,2021,(10):1854-1858 |
| 穴位埋线联合补肾调经汤对多囊卵巢综合征患者性激素水平及代谢指标的影响 |
| Effect of Acupoint Catgut Embedding Combined with Tonifying Kidney and Regulating Meridian Decoction on Sex Hormone Level and Metabolic Index in Patients with Polycystic Ovary Syndrome |
| 投稿时间：2020-11-04 修订日期：2020-11-27 |
| DOI：10.13241/j.cnki.pmb.2021.10.011 |
| 中文关键词: 穴位埋线 补肾调经汤 多囊卵巢综合征 性激素 糖代谢 脂代谢 |
| 英文关键词: Acupoint catgut embedding Tonifying kidney and regulating meridian decoction Polycystic ovary syndrome Sex hormone Glycometabolism Lipid metabolism |
| 基金项目:广东省科技计划项目（20160215） |
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| 中文摘要: |
| 摘要 目的：探讨穴位埋线联合补肾调经汤对多囊卵巢综合征（PCOS）患者性激素水平及糖脂代谢指标的影响。方法：选择2018年10月至2019年9月广州中医药大学附属宝安区中医院妇科门诊收治的116例PCOS患者，按随机数字表法将患者分为两组，各58例。对照组采用炔雌醇环丙孕酮片治疗3个月，观察组给予补肾调经汤和穴位埋线治疗3个月。观察两组疗效、治疗前后体质量指数（BMI）、性激素水平和糖脂代谢指标的差异。结果：观察组治疗总有效率高于对照组（P＜0.05）。两组治疗后BMI、睾酮（T）、促黄体生成素（LH）均下降，且观察组低于对照组（P＜0.05），两组治疗后促卵泡激素（FSH）比较无统计学差异（P＞0.05）。两组治疗后总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）、空腹血糖（FPG）、空腹胰岛素（FINS）、胰岛素抵抗指数（HOMA-IR）均有所下降，且观察组低于对照组，高密度脂蛋白胆固醇（HDL-C）有所升高，且观察组高于对照组（P＜0.05）。结论：穴位埋线联合补肾调经汤治疗PCOS的疗效满意，能够控制体重，可改善PCOS患者性激素水平和糖脂代谢紊乱。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of acupoint catgut embedding and tonifying kidney and regulating meridian decoction on sex hormone level and glucose and lipid metabolism in patients with polycystic ovary syndrome (PCOS). Methods: 116 PCOS patients admitted to Outpatient Department of Baoan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine from October 2018 to September 2019 were selected and randomly divided into two groups by random number table method, 58 cases in each group. The control group was treated with ethinylestradiol cyproterone tablets for 3 months, while the observation group was treated with tonifying kidney and regulating meridian decoction and acupoint catgut embedding for 3 months. The therapeutic effect, body mass index (BMI), sex hormone level and glucose and lipid metabolism between the two groups before and after treatment were observed. Results: The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05). After treatment, the BMI, testosterone(T), luteinizing hormone(LH) decreased in the two groups, and the observation group was lower than the control group(P<0.05), There was no significant difference in follicle-stimulating hormone (FSH) between the two groups after treatment(P＞0.05). After treatment, the total cholesterol(TC), triglyceride(TG), low density lipoprotein cholesterol (LDL-C), fasting plasma glucose(FPG), fasting insulin(FINS), homeostasis model assessment for insulin resistance(HOMA-IR) decreased in the two groups, and the observation group was lower than the control group, the high density lipoprotein cholesterol(HDL-C) increased, and the observation group was higher than the control group(P<0.05). Conclusion: Acupoint catgut embedding combined with tonifying kidney and regulating meridian decoction has a satisfactory effect on PCOS, which can control body weight and improve the serum sex hormone level and the disorder of glucose and lipid metabolism of PCOS patients. |
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