文章摘要
王芳芳,王新春,隋 霜,白治爱,季飞飞.妊娠期糖尿病妇女产后糖代谢转归调查及糖代谢异常的危险因素分析[J].,2022,(3):535-538
妊娠期糖尿病妇女产后糖代谢转归调查及糖代谢异常的危险因素分析
Investigation on the Outcome of Postpartum Glucose Metabolism and Analysis of Risk Factors of Abnormal Glucose Metabolism in Pregnant Women with Gestational Diabetes Mellitus
投稿时间:2021-05-06  修订日期:2021-05-31
DOI:10.13241/j.cnki.pmb.2022.03.028
中文关键词: 妊娠期糖尿病  糖代谢转归  产后  糖代谢异常  危险因素
英文关键词: Gestational diabetes mellitus  Glucose metabolism returns  Postpartum  Abnormal glucose metabolism  Risk factors
基金项目:新疆维吾尔自治区人民医院科技引进创新项目(20160310)
作者单位E-mail
王芳芳 新疆维吾尔自治区人民医院产科 新疆 乌鲁木齐 830001 w1782424@163.com 
王新春 新疆维吾尔自治区人民医院产科 新疆 乌鲁木齐 830001  
隋 霜 新疆维吾尔自治区人民医院产科 新疆 乌鲁木齐 830001  
白治爱 新疆维吾尔自治区人民医院产科 新疆 乌鲁木齐 830001  
季飞飞 新疆维吾尔自治区人民医院产科 新疆 乌鲁木齐 830001  
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中文摘要:
      摘要 目的:研究妊娠期糖尿病(GDM)妇女产后糖代谢转归情况及糖代谢异常的危险因素。方法:选取2018年6月~2020年6月期间本院收治的GDM患者119例为研究对象,对患者产后进行随访观察,调查患者的糖代谢转归情况。根据患者的糖代谢转归情况将患者分为糖代谢正常组(64例)和糖代谢异常组(55例),采用单因素分析的方法对两组患者的人口学资料、临床检测数据等进行统计比较,并采用多因素Logistic回归分析影响GDM患者产后糖代谢异常的危险因素。结果:119例GDM患者中产后12周内糖代谢异常患者55例,糖代谢异常发生率为46.22%。经单因素分析显示:糖代谢异常组年龄、孕前体质指数(BMI)、糖尿病家族史患者占比均高于糖代谢正常组,产后每天运动时间少于糖代谢正常组(P<0.05)。经多因素Logistic回归分析显示:年龄≥35岁、孕前BMI≥25 kg/m2、糖尿病家族史、产后每天运动时间<1 h是GDM患者产后糖代谢异常的危险因素。结论:GDM患者产后有较高的糖代谢异常发生率,患者产后糖代谢异常受多种因素影响,临床工作中应尽早根据相关因素制定干预方案。
英文摘要:
      ABSTRACT Objective: To study and investigate the outcome of postpartum glucose metabolism and the risk factors of abnormal glucose metabolism in women with gestational diabetes mellitus (GDM). Methods: 119 patients with GDM in our hospital from June 2018 to June 2020 were selected as the research objects, and the patients were followed up after delivery, the glucose metabolism outcome of the patients were investigated. According to the outcome of glucose metabolism, the patients were divided into normal glucose metabolism group(64 cases) and abnormal glucose metabolism group(55 cases). Univariate analysis was used to compare the demographic data and clinical test data of the two groups, and multivariate Logistic regression was used to analyze the risk factors of abnormal postpartum glucose metabolism in GDM patients. Results: There were 55 cases of abnormal glucose metabolism in 119 GDM patients within 12 weeks postpartum, the incidence rate of abnormal glucose metabolism was 46.22%. By univariate analysis, the age, pre pregnancy body mass index (BMI) and the number of patients with family history of diabetes in the abnormal glucose metabolism group were higher than those in the normal glucose metabolism group, and the daily postpartum exercise time was lower than that in the normal glucose metabolism group(P<0.05). Multivariate logistic regression analysis showed that age≥35 years, pre-pregnancy BMI≥25 kg/m2, family history of diabetes and time to exercise every day after delivery<1 h were risk factors for abnormal glucose metabolism in GDM patients. Conclusion: GDM patients have a higher incidence rate of abnormal glucose metabolism after delivery, abnormal postpartum glucose metabolism in patients is affected by a variety of factors, clinical work should be based on the relevant factors as early as possible to develop intervention programs.
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