文章摘要
翟一蔓,陈 千,邵晓莉,苟 琴,李冬梅,刘文君.体描箱在评估婴幼儿急性下呼吸道感染肺功能改变中的价值[J].,2022,(9):1795-1800
体描箱在评估婴幼儿急性下呼吸道感染肺功能改变中的价值
Value of Body Plethysmography in Assessing the Lung Function of Infants with Acute Lower Respiratory Tract Infection
投稿时间:2021-11-06  修订日期:2021-11-28
DOI:10.13241/j.cnki.pmb.2022.09.039
中文关键词: 婴幼儿  急性下呼吸道感染  体描箱  诊断
英文关键词: Infants  Acute lower respiratory tract infection  Body plethysmography  Diagnosis
基金项目:四川省重大科技专项项目(2019YFS0531)
作者单位E-mail
翟一蔓 西南医科大学附属医院儿科 四川 泸州 646000 zhaiyiman0123@163.com 
陈 千 西南医科大学附属医院儿科 四川 泸州 646000  
邵晓莉 西南医科大学附属医院儿科 四川 泸州 646000四川省出生缺陷临床医学研究中心 四川 泸州 646000  
苟 琴 西南医科大学附属医院儿科 四川 泸州 646000四川省出生缺陷临床医学研究中心 四川 泸州 646000  
李冬梅 西南医科大学附属医院儿科 四川 泸州 646000四川省出生缺陷临床医学研究中心 四川 泸州 646000  
刘文君 西南医科大学附属医院儿科 四川 泸州 646000四川省出生缺陷临床医学研究中心 四川 泸州 646000  
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中文摘要:
      摘要 目的:探讨体描箱评估婴幼儿急性下呼吸道感染(ALRTI)肺功能改变的价值。方法:收集2020年10月至2021年6月于我院收治的76例ALRTI婴幼儿,根据感染部位分为肺炎组与支气管炎组,根据有无喘息症状分为喘息性组和非喘息性组,采用体描箱测量潮气呼吸参数、体描箱特有指标,分别进行两组间肺功能比较,分析各参数之间相关性,采用受试者工作特征(ROC)曲线评估体描特有指标在婴幼儿ALRTI中的诊断价值。结果:肺炎组与支气管炎组比较,各潮气呼吸参数及功能残气量(FRCp)无明显差异(P>0.05),而有效气道阻力(Reff)和特殊有效气道阻力(sReff)有明显差异(P<0.05);对于喘息性组与非喘息性组,sReff有显著差异(P<0.05);76例ALRTI患儿潮气量(VT)与每公斤体质量潮气量(VT/kg)呈正相关(P<0.05),VT、VT/kg均与呼吸频率(RR)、达峰时间比(TPTEF/TE)呈负相关(P<0.05), TPTEF/TE与达峰容积比(VPTEF/VE)呈正相关(P<0.05),sReff与FRCp、Reff均呈正相关(P<0.05);ROC曲线显示,sReff在诊断肺炎与支气管炎、喘息性和非喘息性的价值最高,ROC曲线下面积分别为0.704、0.688。结论:对于ALRTI患儿,体描箱参数Reff和sReff可帮助判断感染部位,且sReff可直接反映小气道阻塞情况,诊断价值较高,值得临床推广应用。
英文摘要:
      ABSTRACT Objective: To explore the value of body plethysmography in assessing the lung function of infants with acute lower respiratory tract infection (ALRTI). Methods: 76 infants with ALRTI who were treated in our hospital from October 2020 to June 2021 were collected. They were divided into pneumonia group and bronchitis group according to the site of infection. They were divided into wheezing group and non wheezing group according to the presence or absence of wheezing symptoms. The tidal breathing parameters and specific indexes of body plethysmography were measured by the body plethysmography. The lung function between the two groups was compared, and the correlation between the parameters was analyzed, receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of specific indexes of body plethysmography in ALRTI with infant. Results: There were no significant differences in tidal respiratory parameters and funct.Res.Cap.Pleth (FRCp) between pneumonia group and bronchitis group (P>0.05), but there were significant differences in resistance effective (Reff) and specific resistance effective (sReff) (P<0.05). There was significant difference in sReff between wheezing group and non wheezing group (P<0.05). The tidal volume (VT) of 76 infants with ALRTI was positively correlated with the tidal volume per kilogram(VT/kg)(P<0.05), VT and VT/kg were negatively correlated with respiratory rate (RR) and ratio of time to peak tidal expiratory flow to total expiratory time(TPTEF/TE)(P<0.05), TPTEF/TE was positively correlated with volume at PTEF/Expiratory volume(VPTEF/VE)(P<0.05), sReff was positively correlated with FRCp and Reff(P<0.05). ROC curve showed that sReff had the highest value in the diagnosis of pneumonia and bronchitis, wheezing and non wheezing, and the areas under ROC curve were 0.704 and 0.688 respectively. Conclusion: For infants with ALRTI, the parameters Reff and sReff of body plethysmography can help to judge the location of infection, and sReff can directly reflect the situation of small airway obstruction. It has high diagnostic value and is worthy of clinical application.
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