| 郭 燕,李六一,芶开来,胡 川,任雪倩.SMI对缺血性脑卒中患者颈动脉粥样硬化斑块新生血管的评估价值分析[J].,2024,(19):3761-3764 |
| SMI对缺血性脑卒中患者颈动脉粥样硬化斑块新生血管的评估价值分析 |
| Value of SMI in Evaluating Carotid Atherosclerotic Plaque Neovascularization in Patients with Ischemic Stroke |
| 投稿时间：2024-04-27 修订日期：2024-05-22 |
| DOI：10.13241/j.cnki.pmb.2024.19.042 |
| 中文关键词: 超微血管成像 缺血性脑卒中 颈动脉粥样硬化 斑块 新生血管 |
| 英文关键词: Superb micro-vascular imaging Ischemic stroke Carotid atherosclerosis Plaque Neovascularization |
| 基金项目:重庆市科委前沿研究项目（cstc2017jcyjAX0403）；重庆医科大学附属璧山医院院级科研项目（BYKY2023006） |
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| 中文摘要: |
| 摘要 目的：观察超微血管成像（SMI）对缺血性脑卒中患者颈动脉粥样硬化斑块新生血管的评估价值。方法：选取2022年1月~2023年12月缺血性脑卒中伴有颈动脉粥样硬化斑块患者100例，所有患者均行SMI检查与斑块病理组织检查，比较两种方法对斑块内新生血管的检出情况，另外根据斑块病理组织检查结果将其分为观察组（存在新生血管）与对照组（无新生血管），比较两组SMI评分与斑块特征。结果：本研究纳入100例患者中，经病理检查诊断存在新生血管81例，经SMI检查诊断存在新生血管78例，且SMI检查诊断新生血管与病理检查结果比较Kappa检验一致性系数为0.78；ROC曲线显示SMI诊断新生血管的灵敏度、特异度及准确性分别为93.83%、89.47%、93.00%。SMI评分为2分的新生血管MVD值最高，SMI评分为1分次之，SMI评分为0分MVD值最低（P＜0.05）。观察组SMI评分、斑块长度、厚度、钙化及纤维化程度均高于对照组（P＜0.05），且多因素Logistic回归分析发现，SMI评分、斑块厚度及钙化程度是缺血性脑卒中患者颈动脉粥样硬化斑块新生血管形成的独立影响因素（P＜0.05）。Spesrman相关性分析显示，SMI评分、斑块厚度及钙化程度与新生血管形成均成正相关（P＜0.05）。结论：SMI能准确评估缺血性脑卒中患者颈动脉粥样硬化斑块新生血管的形成情况，且SMI评分、斑块厚度及钙化程度均与缺血性脑卒中患者颈动脉粥样硬化斑块新生血管生成密切相关，建议予以密切关注。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the value of superb micro-vascular imaging (SMI) in evaluating carotid atherosclerotic plaque neovascularization in patients with ischemic stroke. Methods: One hundred patients with ischemic stroke and carotid atherosclerotic plaques from January 2022 to December 2023 were selected. All patients underwent SMI examination and histopathological examination of plaque. The detection of neovascularization in the plaque was compared between the two methods. According to pathological results, the patients were divided into observation group (with neovascularization) and control group (without neovascularization). SMI scores and plaque characteristics of the two groups were compared. Results: Among the 100 patients included in this study, 81 patients were diagnosed with neovascularization through pathological examination and 78 patients were diagnosed with neovascularization through SMI examination. Kappa test showed that the coefficient of consistency between SMI examination and pathological examination was 0.78. ROC curves indicated that the sensitivity, specificity and accuracy of SMI for diagnosing neovascularization were 93.83%, 89.47% and 93.00%. The MVD value of neovascularization with SMI score of 2 was the highest, followed by that with SMI score of 1. The MVD value of neovascularization with SMI score of 0 was the lowest(P<0.05). SMI score, plaque length, thickness, calcification and fibrosis degree of the observation group were higher than those of the control group(P<0.05). Multivariate logistic regression analysis found that SMI score, plaque thickness and calcification degree were independent influencing factors of carotid atherosclerotic plaque neovascularization in patients with ischemic stroke(P<0.05). Spesrman correlation analysis showed that SMI score, plaque thickness and calcification degree were positively correlated with neovascularization(P<0.05). Conclusion: SMI can help to evaluate carotid atherosclerotic plaque neovascularization in patients with ischemic stroke accurately. SMI score, plaque thickness and calcification degree are closely related to carotid atherosclerotic plaque neovascularization in patients with ischemic stroke. Therefore, it is recommended to pay close attention to these factors. |
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