| 王 斌,朱 进,袁 彪,唐玉平,沈 杨,张显军.改良自体颅骨缺损修补术在创伤性脑损伤患者中的应用效果及对神经功能、生活能力的影响[J].,2025,(18):2949-2955 |
| 改良自体颅骨缺损修补术在创伤性脑损伤患者中的应用效果及对神经功能、生活能力的影响 |
| Effect of Modified Autologous Skull Defect Repair in Patients with Traumatic Brain Injury and its Influence on Neurological Function and Living Ability |
| 投稿时间：2025-03-16 |
| DOI：10.13241/j.cnki.pmb.2025.18.010 |
| 中文关键词: 改良自体颅骨 颅骨缺损修补术 创伤性脑损伤 神经功能 生活能力 |
| 英文关键词: Modified autologous Skull defect repair Traumatic brain injury Neurological function Living ability |
| 基金项目:毕节市科技计划项目[毕科合〔2023）31号] |
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| 中文摘要: |
| 摘要 目的：观察改良自体颅骨缺损修补术在创伤性脑损伤患者中的应用效果及对神经功能、生活能力的影响。方法：纳入我院2022年3月至2024年8月期间收治的104例创伤性脑损伤患者，根据不同应用材料分为A组[37例，聚醚醚酮材料（poly ether ether ketone, PEEK）颅骨缺损修补]、B组（35例，传统钛网颅骨缺损修补）和C组（32例，改良自体颅骨缺损修补）。对比三组围术期指标、神经功能、日常生活活动能力、生活质量、满意度和术后并发症发生情况。结果：三组患者手术时间、手术出血量、术后住院时间组间对比未见差异（P>0.05）。A组、B组、C组住院费用依次下降（P<0.05）。三组患者术后3个月、6个月日常生活活动能力量表（activity of daily living, ADL）评分升高，美国国立卫生研究院卒中量表（National Institutes of Health Stroke Scale, NIHSS）评分下降（P<0.05）。三组患者术后6个月生理职能、社会职能、心理职能以及物质生活对比未见差异（P>0.05）。C组患者的总满意率高于A组和B组（P<0.05）。C组患者的并发症总发生率低于A组、B组（P<0.05）。结论：PEEK、传统钛网、改良自体颅骨用于颅骨缺损修补术，手术时间、手术出血量、术后住院时间相当，且可减轻神经功能损伤，提高生活能力，改善患者的生活质量，但PEEK费用偏贵，传统钛网满意度偏低、术后并发症发生率相对偏高。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of modified autologous skull defect repair in patients with traumatic brain injury and its influence on neurological function and living ability. Methods: 104 patients with traumatic brain injury who were admitted to our hospital from March 2022 to August 2024 were included, they were divided into Group A [37 cases, poly ether ether ketone (PEEK) skull defect repair], Group B (35 cases, traditional titanium mesh skull defect repair), and Group C (32 cases, modified autologous skull defect repair). Perioperative indicators, neurological function, activity of daily living, quality of life, satisfaction, and incidence of postoperative complications were compared among three groups. Results: There were no differences in the operation time, operation blood loss and postoperative hospital stay among the three groups (P>0.05). The hospitalization costs of Group A, Group B and Group C decreased successively (P<0.05). Activity of Daily Living (ADL) scores at 3 and 6 months after surgery increased among three groups, while National Institutes of Health Stroke Scale (NIHSS) scores decreased (P<0.05). There was no significant difference in physiological function, social function, psychological function, and material life among the three groups at 6 months after surgery (P>0.05). The overall satisfaction rate in Group C was higher than that of Group A and Group B (P<0.05). The overall incidence of complications in Group C was lower than that in Group A and Group B (P<0.05). Conclusion: PEEK, traditional titanium mesh, and modified autologous skull are used in skull defect repair, operation time, operation blood loss and postoperative hospital stay are comparable, they can also reduce neurological function damage, improve living ability, and enhance the quality of life of patients, however, PEEK is relatively expensive, the satisfaction of traditional titanium mesh is low, andincidence of postoperative complications are relatively high. |
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