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| 血管阻力及子宫动脉血流参数预测早期妊高症并发先兆子痫的效能分析 |
| Predictive the effect of vascular resistance and uterine arterial blood flow parameters on the prediction of preeclampsia in patients with early pregnancy induced hypertension |
| 投稿时间：2021-05-20 修订日期：2021-05-20 |
| DOI： |
| 中文关键词: 血管阻力 子宫动脉 妊高症 先兆子痫 |
| 英文关键词: Vascular resistance Uterine artery Pregnancy induced hypertension Preeclampsia |
| 基金项目: |
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| 摘要点击次数: 206 |
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| 中文摘要: |
| 目的：探讨血管阻力(TVR)及子宫动脉血流参数预测早期妊高症并发先兆子痫的效能。方法：对2018年4月-2020年8月102例医院确诊为早期妊高症患者的临床资料进行回顾性分析,记为研究组；选择同时期的健康孕妇72例记为对照组。对比研究组和对照组TVR、子宫动脉搏动指数(PI)、阻力指数(RI)及收缩期峰值流速/舒张末期流速(S/D)等参数值。统计研究组先兆子痫并发率；对比研究组并发先兆子痫者和未并发先兆子痫者TVR、RI、PI、S/D等参数值；评价TVR、RI、PI、S/D及四者联合对早期妊高症并发先兆子痫的预测效能。结果：研究组TVR、RI、PI、S/D参数值均显著高于对照组(P＜0.05)；研究组先兆子痫并发率为10.78%；研究组并发先兆子痫者TVR、RI、PI、S/D参数值均显著高于未并发者(P＜0.05)；TVR、RI、PI、S/D预测早期妊高症并发先兆子痫的最佳截断点为1204.64达因×s/cm5、1.43、0.72、3.35,四者联合预测早期妊高症并发先兆子痫的灵敏度、特异度和AUC均最高,分别为90.91%、82.42%和0.909。结论：早期妊高症患者TVR、RI、PI、S/D参数值较高,且并发先兆子痫风险较高,早期妊高症并发先兆子痫者TVR、RI、PI、S/D参数值较高,且TVR、RI、PI、S/D及四者联合对预测早期妊高症并发先兆子痫者的效能理想,可应用于临床。 |
| 英文摘要: |
| Objective: To explore the predictive effect of vascular resistance (TVR) and uterine arterial blood flow parameters on the prediction of preeclampsia in patients with early pregnancy induced hypertension. Methods: The clinical data of 102 patients with severe Parkinson"s disease diagnosed by the hospital from April 2018 to August 2020 were analyzed retrospectively and recorded as the study group, the selection of 72 healthy pregnant women in the same period as the control group. The TVR, uterine artery pulsatility index (PI), resistance index (RI) and peak systolic velocity/ end-diastolic velocity (S/D) of the study group and control group were compared, the incidence of preeclampsia in thel study group was calculated, the parameters of TVR, RI, PI, S/D between preemptive seizures and without preemptive seizures in the study group were compared, the predictive efficacy of TVR, RI, PI, S/D and combined in the prediction of preeclampsia with early pregnancy induced hypertension was evaluated. Results: The parameters of TVR, RI, PI and S/D in the study group were significantly higher than that in the control group (P <0.05). The incidence of preeclampsia in the study group was 10.78%. The parameters of TVR, RI, PI, S/D of preemptive seizures in the study group were significantly higher than those of without preemptive seizures (P < 0.05). The best cut-off points of TVR, RI, PI, S/D for preeclampsia is 1204.64 dyne×s/cm5, 1.43, 0.72, 3.35, the combined method had the highest sensitivity, specificity and AUC for predicting of preeclampsia in patients with early pregnancy induced hypertension, which were 90.91%, 82.42% and 0.909, respectively. Conclusion: The value of TVR, RI, PI and S/D in patients with early pregnancy induced hypertension is high, and the risk of preeclampsia is high. The parameter value of TVR, RI, PI and S/D of preeclampsia is higher in patients with severe Parkinson"s disease. and combined can predict of preeclampsia in patients with severe Parkinson"s disease, and it can be used in clinical practice. |
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