| Objective: To investigate the therapeutic effect of postpartum Zhuyu Capsule Combined with mifepristone on postpartum lochia. Methods: 128 cases of postpartum lochia in Qinghai Red Cross Hospital from June 2017 to December 2019 were selected, they were divided into control group （n=64）, observation group（n=64）according to random number table method. The control group was treated with mifepristone, and the the observation group was additionally treated with postpartum Zhuyu Capsule on the basis of the control group. The curative effect, uterine three diameter, coagulation function index, average lochia cleaning time, lochia volume and adverse reactions were compared between the two groups. Results: The total effective rate of the observation group was 93.75% (60/64), which was higher than 76.56% (49/64) of the control group (P<0.05). 2 weeks after treatment, the uterine three diameter in the two groups was smaller than that before treatment, and the observation group was smaller than the control group (P<0.05). There was no difference in adverse reactions between the two groups (P>0.05). 2 weeks after treatment, fibrinogen (FIB), prothrombin time (PT) , activated partial thromboplastin time (APTT) and thrombin time (TT) in the two groups decreased, and the observation group was lower than the control group (P<0.05). The lochia volume in the observation group was less than that in the control group, and the average lochia cleaning time in the observation group was shorter than those in the control group (P<0.05). There was no significant difference in adverse reactions between the two groups (P>0.05). Conclusion: The combination of postpartum Zhuyu Capsule and mifepristone has reliable curative effect, can effectively prevent the Lulu, promote the uterine recovery, improve the coagulation function of the body, and has good safety. |
