| Objective: To explore the efficacy of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars and analyze its influencing factors. Methods: A total of 98 patients with depressed acne scars who were treated in our hospital from July 2018 to August 2020 were selected as the research objects. All patients were treated with ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation, symptom scores and scar area of patients before and after treatment were analyzed. At the same time, the patients were divided into effective group and control group according to the treatment effect after treatment. Binary Logistic regression was used to analyze the influencing factors of the efficacy of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars. Results: After the patients were treated with ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation, the symptom scores and scar area were significantly reduced (P﹤0.05), and the total effective rate reached 79.59% at 3 months after treatment. The patients with effective treatment were regarded as the effective group (n=78), and the patients with ineffective treatment were regarded as the control group (n=20). The single factor analysis results showed that the age, self-rating depression scale score, self-rating anxiety scale score and disease course of patients of effective group were significantly lower than those of patients of control group (P﹤0.05). The proportion of patients complicated with other skin diseases in effective group was significantly less than that in control group (P﹤0.05). Binary Logistic regression results showed that the patient’s age (OR=18.225, 95%CI: 6.805～31.589), self-rating depression scale score (OR=7.090, 95%CI: 2.430～21.148), self-rating anxiety scale (OR=1.022, 95%CI: 1.008～1.036), disease course (OR=3.049, 95%CI: 1.346～6.184) and complicated with other skin diseases (OR=14.318, 95%CI: 5.234～18.595) were the influential factors of efficacy (P﹤0.05). Conclusion: The ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation in the treatment of depressed acne scars, can effectively improve the patient''s symptoms, clinical effect is remarkable, the patient''s age, mental state, disease course and complicated with other skin diseases will affect the treatment effect of ultra-pulse CO2 lattice laser combined with photonic skin rejuvenation for depressed acne scars. |
