| Objective: To investigate the effect of hexuemingmu tablet combined with whole retina laser photocoagulation (PRP) on visual acuity, hemorheology and choroidal thickness in patients with diabetes retinopathy (DR). Methods: 60 patients with DR who received treatment in Anhui No.2 Provincial People’s Hospital from March 2018 to December 2019 were selected, and they were randomly numbered by computer and divided into control group (odd, n=30) and study group (even, n=30) in odd-even order. On the basis of conventional hypoglycemic treatment for the two groups, the control group received PRP treatment. The patients in the study group received hexuemingmu tablet combined with PRP treatment. The total clinical response rate of the two groups was compared, and the changes of visual acuity, hemorheology and choroid thickness were observed before and after treatment. Results: The total clinical effective rate in the study group was higher than that in the control group (P<0.05). After treatment, naked eye vision, visual field and visual acuity were increased in two groups, and the degree of increase in the study group was greater than that in the control group (P<0.05). After treatment, plasma viscosity (PV), erythrocyte aggregation index (AI), whole blood high shear viscosity (NBH), whole blood low shear viscosity (NBL) and erythrocyte sedimentation rate (ESR) decreased in two groups, and the decrease degree in the study group was greater than that in the control group (P<0.05). After treatment, the inferior choroid thickness (SFCT), inferior choroid thickness (ICT), superior choroid thickness (SCT), nasal choroid thickness (NCT) and temporal choroid thickness (TCT) in the macular fovea decreased in two groups, and the decrease degree in the study group was greater than that in the control group (P<0.05). There were no obvious adverse reactions in two groups. Conclusion: Hexuemingmu tablet combined with PRP can effectively improve the visual acuity, hemorheology and choroidal thickness of patients with DR, and the curative effect is safe and reliable. |
