| Objective: To investigate the effects of different intensity aerobic exercise on cardiopulmonary function, vascular endothelial function and quality of life in patients with cardiac dyfunction (CD) after acute myocardial infarction (AMI), in order to provide guidance for clinical intervention of CD after AMI. Methods: A total of 135 patients with CD after AMI admitted to our hospital from May 2022 to May 2023 were selected for prospective study,and divided into group A (n=45), group B (n=45) and group C (n=45) by random number table method.Group A received conventional treatment,and group B received moderate intensity aerobic exercise on the basis of group A.Group C performed high intensity intermittent aerobic exercise on the basis of group A,and compared the cardiac function index,lung function, vascular endothelial function and quality of life of the three groups.Results:After intervention,left ventricular end systolic diameter(LVESD) and left ventricular end diastolic diameter (LVEDD) in the three groups were decreased (P<0.05), and left ventricular ejection fraction(LVEF) was increased (P<0.05),LVESD and LVEDD in groups B and C were lower than those in group A (P<0.05), and LVEF was higher (P<0.05),LVESD and LVEDD of group C were lower than those of group B (P<0.05), and the LVEF of group C was higher than that of group B(P<0.05). After the intervention, the forced vital capacity (FVC), the forced expira-tory volume in 1 second(FEV1) /FVC (FEV1/FVC), and the maximal voluntary ventilation (MVV) in the three groups were increased (P<0.05), and those in groups B and C were higher than those in group A (P<0.05), and those in group C were higher than those in group B (P<0.05). After intervention, endothelin-1 (ET-1) decreased in the three groups (P<0.05),nitric oxide (NO),endothelium mediated flow-mediated dilation(FMD) and nitroglycerin mediated nitroglycerin-mediateddilation(NMD) increased(P<0.05),and ET-1 in groups B and C was lower than that in group A (P<0.05). NO, FMD and NMD were higher (P<0.05), ET-1 in group C was lower than that in group B (P<0.05), and NO, FMD and NMD were higher (P<0.05). After the intervention, the score of Seattle Angina Questionnaire(SAQ) in the three groups was increased (P<0.05), and the score in group B and C was higher than that in group A (P<0.05), and the score in group C was higher than that in group B (P<0.05).Conclusion:The effect of high intensity intermittent aerobic exercise in CD patients after AMI is good,which can effectively improve the cardiopulmonary function,vascular endothelial function,and improve the quality of life,which is worthy of clinical reference and application. |
