| 朱智全,郭广红,袁新红,杨文海,闫 华.血小板活化指标及血小板参数在乙肝肝硬化患者中的检测价值研究[J].,2017,17(24):4688-4690 |
| 血小板活化指标及血小板参数在乙肝肝硬化患者中的检测价值研究 |
| Study on Detection Value of Platelet Activation Indexes and Platelet Parameters in Patients with Hepatitis B-induced Cirrhosis |
| 投稿时间：2016-12-26 修订日期：2017-01-20 |
| DOI：10.13241/j.cnki.pmb.2017.24.021 |
| 中文关键词: 血小板活化指标 血小板参数 乙肝肝硬化 检测价值 |
| 英文关键词: Platelet activation indexes Platelet parameters Hepatitis B-induced cirrhosis Detection value |
| 基金项目:北京市科委--首都医学发展科研基金项目（2007-3024） |
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| 中文摘要: |
| 摘要 目的：研究血小板活化指标及血小板参数在乙肝肝硬化患者中的检测价值。方法：选取2015年11月~2016年8月期间于本院进行诊治的40例乙肝肝硬化患者为观察组，同时期的40名体检结果为健康的人员为对照组，检测与比较两组同龄人员的血小板活化指标及血小板参数，并比较不同分期乙肝肝硬化患者的上述两方面检测结果。结果：观察组的PLT低于对照组，其他血小板参数及血小板活化指标均高于对照组，且不同分期乙肝肝硬化患者的上述两方面检测结果也存在明显差异，P均＜0.05，比较结果间均有显著性差异。结论：乙肝肝硬化患者的血小板活化指标及血小板参数表达明显异常，且不同肝硬化分期患者的表达水平也存在显著性差异，因此应加强对乙肝肝硬化患者上述指标的监测。 |
| 英文摘要: |
| ABSTRACT Objective: To study the detection value of platelet activation indexes and platelet parameters in patients with hepatitis B-induced cirrhosis. Methods: 40 patients with hepatitis B-induced cirrhosis in our hospital from November 2015 to August 2016 were selected as the observation group. 40 healthy subjects went through physical examination during the same period were chosen as the control group. The platelet activation indexes and platelet parameters of subjects with same age in two groups were detected and compared. The detection results of the two items in patients with different stages of hepatitis B-induced cirrhosis were compared, too. Results: The PLT of observation group was lower than that of control group，while the other platelet parameters and platelet activation indexes were all higher than those of control group. The detection results of two items in patients with different stages of hepatitis B-induced cirrhosis were with significant differences, all P＜0.05. Conclusion: The platelet activation indexes and platelet parameters in patients with hepatitis B-induced cirrhosis are obviously abnormally expressed. There are significant differences among the detection results in patients with different stages. Therefore, surveillance of those indexes in patients with hepatitis B-induced cirrhosis should be strengthened. |
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