| 汪天杰1 李槿年1 江定丰2 余为一1.禽流感病毒血凝素蛋白的结构、功能与表达[J].现代生物医学进展英文版,2006,6(4):61-62. |
| 禽流感病毒血凝素蛋白的结构、功能与表达 |
| Structure and Bioloyical Function of Hemagglutinin Glycoprotein of AvianInfluenza Virus and its Expression |
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| DOI： |
| 中文关键词: 禽流感病毒 血凝素蛋白 结构 功能 表达 |
| 英文关键词: avian influenza virus( AIV) hemagglutinin ( HA) structure biological function expression |
| 基金项目:省科技攻关项目 |
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| 中文摘要: |
| 血凝素蛋白( HA) 既是一种重要吸附蛋白, 介导禽流感病毒吸附和穿入宿主细胞而发挥致病作用, 也是一种良好的保
护性抗原, 对宿主抵抗禽流感起到了决定性保护作用。研究HA 蛋白对揭示禽流感病毒的致病机理和免疫防治禽流感均具有重
要意义。本文重点概述了HA 蛋白的结构、功能和蛋白表达方面的研究进展, 并对HA 蛋白在禽流感疫苗中的应用进行了探讨。 |
| 英文摘要: |
| Hemaglutinin ( HA) is an important absorbent protein and effectiv protective antigen of AIV. It not only mediates AIV to
adsorb and penetrate cells, but also makes the host produce immunity against AIV. Studing HA have a vital significance to reveal pathogenic
mechanism of AIV and immunoprevention AI. This article reviewed structure, biological function and expression of HA. The application of HA in
AI vaccine was also discussed. |
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