| 吴丽蓉1 唐卫军2△ 吕燕3 李慧4 马荣1.感觉再训练及口服弥可保片剂对周围神经修复术后
患者感觉功能的影响[J].现代生物医学进展英文版,2014,14(17):3304-3307. |
| 感觉再训练及口服弥可保片剂对周围神经修复术后
患者感觉功能的影响 |
| Impacts of of Sensory Reeducation and Oral Intake of Methycobal onPatients' Sensory Function After Peripheral Nerve Regeneration |
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| DOI： |
| 中文关键词: 感觉再训练 弥可保 周围神经修复术 感觉功能 |
| 英文关键词: Sensory retraining Methycobal Peripheral nerve repair Sensory function |
| 基金项目: |
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| 中文摘要: |
| 摘要目的：探讨感觉再训练及口服弥可保片剂对周围神经修复术后患者感觉功能的影响。方法：选取2009 年10 月至2011 年10
月我院收治的腕部损伤患者128 例，随机分为A、B、C、D四组，每组各32 例，在神经修复术及常规治疗的基础上，D 组不采取其
他任何措施治疗；C 组给予弥可保片剂口服治疗；B 组采取感觉再训练治疗；A组采取感觉再训练联合弥可保片剂口服治疗。对比
患者术后1 年及2 年的感觉功能恢复情况及m2-PD 检测结果。结果：A、B、C 组术后1 年及2 年的感觉功能分级情况均优于D
组，差异有统计学意义（P<0.05）。其中，以A 组与D 组相比，差异最为显著（P<0.05）。并且，A 组的感觉功能随着时间的延长不断
改善。A、B、C 组的m2-PD 检测结果均优于D 组，差异有统计学意义（P<0.05）。其中，A组术后1 年及2 年的检测结果分别为
（6.79± 2.08）mm、（4.98± 2.05）mm，相比于D 组的（13.31± 1.64）mm、（11.94± 2.37）mm，差异最为显著（P<0.05）；且术后2 年的的
检测结果明显低于术后1 年，差异有统计学意义（P<0.05）。结论：将感觉再训练与弥可保口服治疗相结合用于周围神经损伤患者
的神经修复术后，治疗效果更佳。能够最大限度的促进患者感觉功能的恢复。 |
| 英文摘要: |
| ABSTRACT Objective:To investigate the impacts of sensory reeducation and oral intake of methycobal on patients' sensory
function after peripheral nerve regeneration. Methods:128 cases of patients with wrist injury in our hospital were selected from October
2009 to October 2011, and were randomly divided into four groups: A, B, C and D, each with 32 cases. Group D did not take any other
therapy, Group C were given oral intake of methycobal, Group B received sensory reeducation, and Group A were treated with oral
intake of methycobal combined with sensory reeducation. After 1 and 2 years, recovery of patients' sensory functions and test results of
m2-PD were compared among the groups. Results：After 1 year and 2 years, sensory functions of Groups A, B, and C were superior to that
of Group D with statistical significance (P<0.05), among which the differences between Group A and Group D were the most notable
(P<0.05). What's more, sensory function of Group A improved continuously with time. Test results of m2-PD of Groups A, B and C were
superior to that of Group D, also with statistical significance (P<0.05). Among which the differences between Group A, (6.79± 2.08)mm
after 1 year and（4.98± 2.05）mm after 2 years，and Group D,（13.31± 1.64）mm and（11.94± 2.37）mm respectively, were the most
remarkable (P<0.05). More importantly, the test results after 2 years were obviously lower than that after 1 year, which was of statistical
significance (P<0.05).Conclusion: Sensory reeducation combined with oral intake of Methycobal proves better therapeutic effect in
patients with peripheral nerve injury, and may maximize the recovery of patients' sensory function. |
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