| 韩康 赵廷宝 卞娜 蔡成魁 杨彤涛 周勇.微波射频保肢术及截肢术治疗胫骨远端骨肉瘤的临床疗效比较[J].现代生物医学进展英文版,2014,14(33):6483-6486. |
| 微波射频保肢术及截肢术治疗胫骨远端骨肉瘤的临床疗效比较 |
| Comparison of the Clinical Efficacy of Limb Salvage with MicrowaveHyperthermia and Amputation in the Treatment of Distal Tibia Osteosarcoma |
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| DOI： |
| 中文关键词: 微波射频保肢术 截肢术 骨肉瘤 胫骨 关节功能 |
| 英文关键词: Microwave Hyperthermia limb salvage Amputation Osteosarcoma Tibia Joint function |
| 基金项目:国家自然科学基金项目(81201633) |
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| 中文摘要: |
| 目的：探讨和比较截肢术和微波射频保肢术治疗胫骨远端骨肉瘤的临床效果和安全性。方法：选择2000 年-2013 年我院收
治的明确诊断为胫骨远端骨肉瘤的患者79 例，其中27 例给予截肢治疗(截肢组)，52 例给予微波射频保肢和重建治疗(保守治疗
组)。评价和比较两组患者的生存情况、局部复发情况、MSTS关节功能评分及并发症的发生情况。结果：两组患者的生存曲线、局
部复发率和并发症的发生率比较均无统计学差异(P>0.05)，但保守治疗组的MSTS 关节功能评分显著高于截肢组，差异有统计学
意义(P<0.05)。结论：微波射频保肢术治疗胫骨远端骨肉瘤患者不会降低患者的生存几率，且在改善患者的关节功能方面有明显
的优势。 |
| 英文摘要: |
| Objective:To compare the clinical effect and safety between patients with distal tibia osteosarcoma treated by limb
salvage with microwave hyperthermia and amputation.Methods:79 patients who were admitted in our hospital from 2000 to 2013 and
diagnosed as distal tibia osteosarcoma were selected, in which 27 patients were treated by amputation and 52 patients were given limb
salvage and allograft reconstructions. The survival situation, local recurrence, MSTS score of joint function as weill as incidence of
complications were evaluated and compared between the two groups.Results:No significant difference was found in the survival curve,
local recurrent rate and incidence of complications between the two groups (P>0.05), but the MSTS score of joint function of patients
treated by limb salvage and allograft reconstruction was predominantly higher than that of patients treated by amputation (P<0.05).Conclusion:Limb salvage using microwave hyperthermia wouldn't reduce the chances of survival of patients with distal tibia
osteosarcoma, and had the advantage of improving patients' joint function. |
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