| Objective:To investigate the relationship between serumparathyroid hormone (PTH) level and nutritional status in patients
with chronic renal failure (CRF) who had taken the maintenance hemodialysis therapy.Methods:98 cases with chronic renal failure
who were treated with maintenance hemodialysis in our hospital fromAugust 2013 to October 2015 were selected as the study group, and
another 69 healthy volunteers were chosen to be the control group. Then the levels of PTH, HDL-C, LDL-C, CRP, BUN, SCr, TP, ALB,
TC, TG and Hb in the serum of patients were detected by radioimmunoassay. The nutritional status of the two groups was evaluated by
mini nutritional assessment (MNA), and the correlation between serumPTH and serumbiochemical parameters was evaluated by Spearman
correlation analysis.Results:The incidence of malnutrition in the study group was 31.63%, which was higher than 13.04% in the
control group (P<0.05); The levels of PTH, HDL-C, LDL-C, CRP, BUN and SCr in the serum of CRF patients with malnutrition were
higher than those of the patients with latent malnutrition and balanced nutrition, and the levels of TP, ALB, TC, TG and Hb were lower
(P<0.05); The levels of PTH, HDL-C, LDL-C, CRP, BUN and SCr in the serumof CRF patients with latent malnutrition were higher than
those of the patients with balanced nutrition, and the levels of TP, ALB, TC, TG and Hb were lower (P<0.05); There was positive relationship
between PTH and BUN and SCr (P<0.05); There was negative relationship between PTH and MNA, TP, TC, TG, CRP and Hb
(P<0.05); There was no correlation between PTH and ALB, HDL-C and LDL-C (P>0.05).Conclusion:High levels of PTH in the serum
CRF patients was the risk factor of malnutrition, which should pay more attention in the clinical field. |
